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The map label for this gene is celR [H]

Identifier: 103486090

GI number: 103486090

Start: 605507

End: 606541

Strand: Reverse

Name: celR [H]

Synonym: Sala_0597

Alternate gene names: 103486090

Gene position: 606541-605507 (Counterclockwise)

Preceding gene: 103486091

Following gene: 103486089

Centisome position: 18.13

GC content: 66.09

Gene sequence:

>1035_bases
ATGGGGCGTCCGCCCTCGGGCAAGCCGACCAGCTTCGACATCGCCTATCTGGCGGGCGTGTCGCAGCCCACTGTGTCGCG
CGCGCTGCGCGGCAGCAAGTCGGTGAGCGCGGCGACGCGCGCCAATATCGAACGCATCGCGCGCGAGCTTAATTACACTG
TCGACAAGAACGCCTCCAGCCTGCGGTCGCAACGCACCCACACGCTCGCTTTGCTCTTTTTCGAGGATCCGACCCCCGAC
GACTCGATGATCAACCCCTTCTTCCTGTCGATGCTGGGGTCGATCACGCGGCAGTGTGCGCTGCGCGGCTATGACCTGCT
CATCAGCTTCCAGCAGATGCACAATGACTGGCACGTCGATTATCAGGACAGCCACCGGTCCGACGGCATCATCCTCCTGG
GCTATGGCGACTATCAGCTTTACCGCGAGAAGCTCGAACATCTGGTCGCGATGGACACCAAGTTCGTGCGCTGGGGATCG
GTGTCGGAGGATGACATCGGGCTGACCGTCGGATCGGACAATATCGGCGCGGGCGAGCAGGCGGGCGCACATCTGATCGA
GATCGGGCGGCGGCGCATCGCTTTCCTCGGCGACGCATCGGATCATGCGCCCGAGTTCCACGACCGCTATCGCGGGCTGT
GCCGCGCGATGCGCGCTGCGGGGATTGAGCCCGACCCGGCGCTGCAACGCAACGCCGTCTCGTCGGAAGCGTCGGGCCAT
GCCGCCGCCAAAACCCTGCTGGACAGCGGCGCGTGTTTCGACGCGATCTTTGCCGCGAGCGACCTGATCGCGATCGGCGC
GATGCGTGCGCTGACCGAAGCGGGGCTGACGATGCCGCAGGACGTCGCGATCATCGGCTTCGACGACATTCCCGCCGCCA
ACCTGACTTCGCCGACGCTGACGACGGTGATGCAGGACATGAAGGGCGCGGGCGAGCTGCTCGTCGACGCGCTGCTCCGC
CGGATCGACGGCGCGGAAGCCGAGCGGCGGGTGCTGCCCACGCGGCTGGTGAAACGGCAGAGCACGGCGGTTTGA

Upstream 100 bases:

>100_bases
CCCCGGCAATGGCTCCGGCCATTGCGCCGCCTCCGCCAGCCGCTTAAATCGGCGTATGATGGCCGGTCGCCACGGGGTGG
CCGCGGCACAGGAGAGGAGC

Downstream 100 bases:

>100_bases
AGGGGGCGGCGTTTTTTGGCGCCGCGGTCGATAATCCTCCCCATCGACTTGCGATGGGGAGGATCGGGCAGGCGCGCAGC
GGCTCGGCCCGCCGCCACGT

Product: LacI family transcription regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 344; Mature: 343

Protein sequence:

>344_residues
MGRPPSGKPTSFDIAYLAGVSQPTVSRALRGSKSVSAATRANIERIARELNYTVDKNASSLRSQRTHTLALLFFEDPTPD
DSMINPFFLSMLGSITRQCALRGYDLLISFQQMHNDWHVDYQDSHRSDGIILLGYGDYQLYREKLEHLVAMDTKFVRWGS
VSEDDIGLTVGSDNIGAGEQAGAHLIEIGRRRIAFLGDASDHAPEFHDRYRGLCRAMRAAGIEPDPALQRNAVSSEASGH
AAAKTLLDSGACFDAIFAASDLIAIGAMRALTEAGLTMPQDVAIIGFDDIPAANLTSPTLTTVMQDMKGAGELLVDALLR
RIDGAEAERRVLPTRLVKRQSTAV

Sequences:

>Translated_344_residues
MGRPPSGKPTSFDIAYLAGVSQPTVSRALRGSKSVSAATRANIERIARELNYTVDKNASSLRSQRTHTLALLFFEDPTPD
DSMINPFFLSMLGSITRQCALRGYDLLISFQQMHNDWHVDYQDSHRSDGIILLGYGDYQLYREKLEHLVAMDTKFVRWGS
VSEDDIGLTVGSDNIGAGEQAGAHLIEIGRRRIAFLGDASDHAPEFHDRYRGLCRAMRAAGIEPDPALQRNAVSSEASGH
AAAKTLLDSGACFDAIFAASDLIAIGAMRALTEAGLTMPQDVAIIGFDDIPAANLTSPTLTTVMQDMKGAGELLVDALLR
RIDGAEAERRVLPTRLVKRQSTAV
>Mature_343_residues
GRPPSGKPTSFDIAYLAGVSQPTVSRALRGSKSVSAATRANIERIARELNYTVDKNASSLRSQRTHTLALLFFEDPTPDD
SMINPFFLSMLGSITRQCALRGYDLLISFQQMHNDWHVDYQDSHRSDGIILLGYGDYQLYREKLEHLVAMDTKFVRWGSV
SEDDIGLTVGSDNIGAGEQAGAHLIEIGRRRIAFLGDASDHAPEFHDRYRGLCRAMRAAGIEPDPALQRNAVSSEASGHA
AAKTLLDSGACFDAIFAASDLIAIGAMRALTEAGLTMPQDVAIIGFDDIPAANLTSPTLTTVMQDMKGAGELLVDALLRR
IDGAEAERRVLPTRLVKRQSTAV

Specific function: Binds to the 14-bp operator sequence 5'-TGGGAGCGCTCCCA- 3' in the upstream regions of cellulase genes; these operator sequences are modulated by cellobiose [H]

COG id: COG1609

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790194, Length=319, Percent_Identity=31.974921630094, Blast_Score=144, Evalue=1e-35,
Organism=Escherichia coli, GI1790369, Length=342, Percent_Identity=30.4093567251462, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI1787948, Length=342, Percent_Identity=27.1929824561404, Blast_Score=108, Evalue=5e-25,
Organism=Escherichia coli, GI1789068, Length=336, Percent_Identity=28.2738095238095, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1790715, Length=322, Percent_Identity=28.5714285714286, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1788474, Length=338, Percent_Identity=28.4023668639053, Blast_Score=95, Evalue=7e-21,
Organism=Escherichia coli, GI1789202, Length=308, Percent_Identity=28.8961038961039, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1787580, Length=334, Percent_Identity=26.6467065868263, Blast_Score=89, Evalue=5e-19,
Organism=Escherichia coli, GI1789456, Length=300, Percent_Identity=29.3333333333333, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI48994940, Length=328, Percent_Identity=25.609756097561, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1786540, Length=161, Percent_Identity=33.5403726708075, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1787906, Length=346, Percent_Identity=23.9884393063584, Blast_Score=71, Evalue=9e-14,
Organism=Escherichia coli, GI1790689, Length=337, Percent_Identity=25.2225519287834, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 37407; Mature: 37276

Theoretical pI: Translated: 6.05; Mature: 6.05

Prosite motif: PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGRPPSGKPTSFDIAYLAGVSQPTVSRALRGSKSVSAATRANIERIARELNYTVDKNASS
CCCCCCCCCCCEEHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCHHH
LRSQRTHTLALLFFEDPTPDDSMINPFFLSMLGSITRQCALRGYDLLISFQQMHNDWHVD
HHHCCCEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHEEHHHHCCCCCCC
YQDSHRSDGIILLGYGDYQLYREKLEHLVAMDTKFVRWGSVSEDDIGLTVGSDNIGAGEQ
CCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHEECCCCCCCCCEEEECCCCCCCCHH
AGAHLIEIGRRRIAFLGDASDHAPEFHDRYRGLCRAMRAAGIEPDPALQRNAVSSEASGH
HHHHHHHHHHHHEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCCH
AAAKTLLDSGACFDAIFAASDLIAIGAMRALTEAGLTMPQDVAIIGFDDIPAANLTSPTL
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCHHH
TTVMQDMKGAGELLVDALLRRIDGAEAERRVLPTRLVKRQSTAV
HHHHHHHCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
GRPPSGKPTSFDIAYLAGVSQPTVSRALRGSKSVSAATRANIERIARELNYTVDKNASS
CCCCCCCCCCEEHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCHHH
LRSQRTHTLALLFFEDPTPDDSMINPFFLSMLGSITRQCALRGYDLLISFQQMHNDWHVD
HHHCCCEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHEEHHHHCCCCCCC
YQDSHRSDGIILLGYGDYQLYREKLEHLVAMDTKFVRWGSVSEDDIGLTVGSDNIGAGEQ
CCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHEECCCCCCCCCEEEECCCCCCCCHH
AGAHLIEIGRRRIAFLGDASDHAPEFHDRYRGLCRAMRAAGIEPDPALQRNAVSSEASGH
HHHHHHHHHHHHEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCCH
AAAKTLLDSGACFDAIFAASDLIAIGAMRALTEAGLTMPQDVAIIGFDDIPAANLTSPTL
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCHHH
TTVMQDMKGAGELLVDALLRRIDGAEAERRVLPTRLVKRQSTAV
HHHHHHHCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10224066 [H]