Blattabacterium sp. (Blattella germanica) str. Bge
Names | Blattabacterium sp. (Blattella germanica) str. Bge |
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Accession numbers | NC_013454, NC_015679 |
Background | Blattabacterium strain Bge is the primary endosymbiont of the cockroach Blattella germanica. It is a Gram-negative maternally inherited bacteria which lives in specialized cells in the host's abdominal fat body. Phylogenetic analyses for the Blattabacterium-cockroach symbiosis supports the hypothesis of co-evolution between symbionts and hosts dating back to more than 140 million years ago. Cockroaches are omnivorous insects, often subsisting on a nitrogen-poor diet, and Blattabacterium have been hypothesized to participate in uric acid degradation, nitrogen assimilation, and nutrient provisioning. Genome sequencing and metabolic reconstruction shows that Blattabacterium can recycle nitrogen from urea and ammonia, which are uric acid degradation products, into glutamate, using urease and glutamate dehydrogenase, and thus would be able to provide its host with some essential amino acids, vitamins and cofactors. The bacterium relies on Pro, Gln and Asn supplied by the host. It encodes the complete machinery to synthesize nucleotides, fatty acids, and the cofactors folic acid, lipoic acid, FAD, NAD, pyridoxine, and riboflavin. Interestingly Blattabacterium strain Bge encodes a complete urea cycle, and the bacteria have urease activity; they could potentially use amino acids efficiently as energy and reducing power sources, generating nitrogen waste in the form of ammonia (adapted from PMID 19911043). (HAMAP: BLASB) |
Taxonomy | |
Kingdom: | Bacteria |
Phylum: | Bacteroidetes |
Class: | Flavobacteria |
Order: | Flavobacteriales |
Family: | Blattabacteriaceae |
Genus: | Blattabacterium |
Species: | sp. |
Strain | Bge |
Complete | Yes |
Sequencing centre | (03-NOV-2009) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA (09-MAR-2009) Institut Cavanilles de Biodiversitat i Biologia Evolutiva, University of Valencia, Poligon 'La Coma' s/n, |
Sequencing quality | Level 6: Finished |
Sequencing depth | NA |
Sequencing method | Sanger, 454 |
Isolation site | "fat body of female adults of the German cockroach, Blattella germanica" |
Isolation country | Spain |
Number of replicons | 2 |
Gram staining properties | Negative |
Shape | Bacilli |
Mobility | No |
Flagellar presence | No |
Number of membranes | 1? |
Oxygen requirements | Aerobic |
Optimal temperature | NA |
Temperature range | Mesophilic |
Habitat | HostAssociated |
Biotic relationship | Symbiotic |
Host name | Blattella germanica |
Cell arrangement | Singles |
Sporulation | Nonsporulating |
Metabolism | NA |
Energy source | NA |
Diseases | NA |
Pathogenicity | No |
Citrate cycle (TCA cycle)
Purine metabolism
Pyrimidine metabolism
Valine, leucine and isoleucine biosynthesis
Lysine biosynthesis
Histidine metabolism
Phenylalanine, tyrosine and tryptophan biosynthesis
Selenocompound metabolism
D-Glutamine and D-glutamate metabolism
Peptidoglycan biosynthesis
C5-Branched dibasic acid metabolism
One carbon pool by folate
Riboflavin metabolism
Vitamin B6 metabolism
Pantothenate and CoA biosynthesis
Lipoic acid metabolism
Folate biosynthesis
Aminoacyl-tRNA biosynthesis
Purine metabolism
Pyrimidine metabolism
Valine, leucine and isoleucine biosynthesis
Lysine biosynthesis
Histidine metabolism
Phenylalanine, tyrosine and tryptophan biosynthesis
Selenocompound metabolism
D-Glutamine and D-glutamate metabolism
Peptidoglycan biosynthesis
C5-Branched dibasic acid metabolism
One carbon pool by folate
Riboflavin metabolism
Vitamin B6 metabolism
Pantothenate and CoA biosynthesis
Lipoic acid metabolism
Folate biosynthesis
Aminoacyl-tRNA biosynthesis