Zymomonas mobilis subsp. mobilis NCIMB 11163
Names | Zymomonas mobilis subsp. mobilis NCIMB 11163 |
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Accession numbers | NC_013355, NC_013356, NC_013357, NC_013358 |
Background | Zymomonas mobilis subsp. mobilis (strain NCIB 11163) is a facultative aerobic, ethanol-producing bacterium. The natural habitat of this organism includes sugar-rich plant saps where the bacterium ferments sugar such as glucose or sucrose into ethanol and carbon dioxide. It is useful in industrial production systems, particularly in production of bioethanol for fuel. Genetically engineered strains that ferment pentoses in addition to naturally utilized hexoses also hold great promise for use in lignocellulosic biomass degradations. Z. mobilis is utilized for the conversion of sugars, particularly xylose, which is not utilized by another common sugar-fermenting organism such as yeast, to ethanol. Since xylose is a common breakdown product of cellulose or a waste component of the agricultural industry, it is an attractive source for ethanol production. Z. mobilis was chosen for this process as it is ethanol-tolerant (up to 120 grams of ethanol per litre) and productive (5-10% more ethanol than Saccharomyces). This bacterium ferments using the Enter-Doudoroff pathway, with the result that less carbon is used in cellular biomass production and more ends up as ethanol, another factor that favors this organism for ethanol production. Besides ethanol, Z. mobilis can produce other high-value chemicals such as sorbitol, levan, or phenylacetylcarbinol and has attracted interest for its unusual membrane steroid content. Lastly, Z. mobilis is regarded as a safe organism and is even used for medicinal purposes, which further facilitates its employment in large-scale biotechnological endeavors. (Adaptated from PMID: 19767433). (EBI Integr8) |
Taxonomy | |
Kingdom: | Bacteria |
Phylum: | Proteobacteria |
Class: | Alphaproteobacteria |
Order: | Sphingomonadales |
Family: | Sphingomonadaceae |
Genus: | Zymomonas |
Species: | mobilis |
Strain | NCIB 11163 |
Complete | Yes |
Sequencing centre | (01-SEP-2009) US DOE Joint Genome Institute, 2800 Mitchell Drive B310, Walnut Creek, CA 94598-1698, USA (07-OCT-2009) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA |
Sequencing quality | Level 6: Finished |
Sequencing depth | NA |
Sequencing method | NA |
Isolation site | fermenting cane juice |
Isolation country | Brazil |
Number of replicons | 4 |
Gram staining properties | Negative |
Shape | Bacilli |
Mobility | Yes |
Flagellar presence | Yes |
Number of membranes | 2 |
Oxygen requirements | Facultative |
Optimal temperature | NA |
Temperature range | Mesophilic |
Habitat | NA |
Biotic relationship | Free living |
Host name | NA |
Cell arrangement | Pairs |
Sporulation | NA |
Metabolism | Ethanol production |
Energy source | NA |
Diseases | NA |
Pathogenicity | No |
Glycolysis / Gluconeogenesis
Citrate cycle (TCA cycle)
Pentose phosphate pathway
Purine metabolism
Pyrimidine metabolism
Alanine, aspartate and glutamate metabolism
Glycine, serine and threonine metabolism
Cysteine and methionine metabolism
Valine, leucine and isoleucine biosynthesis
Lysine biosynthesis
Histidine metabolism
Phenylalanine, tyrosine and tryptophan biosynthesis
Selenocompound metabolism
D-Glutamine and D-glutamate metabolism
D-Alanine metabolism
Peptidoglycan biosynthesis
C5-Branched dibasic acid metabolism
One carbon pool by folate
Thiamine metabolism
Riboflavin metabolism
Vitamin B6 metabolism
Pantothenate and CoA biosynthesis
Biotin metabolism
Lipoic acid metabolism
Folate biosynthesis
Terpenoid backbone biosynthesis
Sulfur metabolism
Aminoacyl-tRNA biosynthesis
Citrate cycle (TCA cycle)
Pentose phosphate pathway
Purine metabolism
Pyrimidine metabolism
Alanine, aspartate and glutamate metabolism
Glycine, serine and threonine metabolism
Cysteine and methionine metabolism
Valine, leucine and isoleucine biosynthesis
Lysine biosynthesis
Histidine metabolism
Phenylalanine, tyrosine and tryptophan biosynthesis
Selenocompound metabolism
D-Glutamine and D-glutamate metabolism
D-Alanine metabolism
Peptidoglycan biosynthesis
C5-Branched dibasic acid metabolism
One carbon pool by folate
Thiamine metabolism
Riboflavin metabolism
Vitamin B6 metabolism
Pantothenate and CoA biosynthesis
Biotin metabolism
Lipoic acid metabolism
Folate biosynthesis
Terpenoid backbone biosynthesis
Sulfur metabolism
Aminoacyl-tRNA biosynthesis