Cronobacter turicensis z3032

Names Cronobacter turicensis z3032
Accession numbers NC_013282, NC_013283, NC_013284, NC_013285
Background Cronobacter turicensis (strain DSM 18703 / LMG 23827 / z3032) is Gram-negative bacterium. Turicensis is the Latin name of Zurich, as the type strain originates from Zurich, Switzerland. It is an opportunistic pathogen that can cause infections such as necrotizing enterocolitis (or coloenteritis), bacteraemia, meningitis and brain abscess/lesions with fatal mortality rates ranging from 40 to 80% . Neonates and infants under two months, born prematurely or with low birth weight are at highest risk for infection most commonly by Cronobacter sp. contaminated powdered infant milk formulas. Notably, Cronobacter sp. is often found in food preparation environments (i.e. chocolate, pasta, cereal and dairy production areas). However, the natural reservoir of this opportunistic pathogen remains unknown. Recently, it has been shown that some strains are able to adhere to human epithelial and endothelial cells. Moreover, Cronobacter sp. is capable of infecting and persisting in human macrophages. It is expected that bacterial virulence factors such as toxins, iron chelators, secretion systems and immune system evasion mechanisms are involved in the infection process. (Adaptated from PMID: 19609963). (EBI Integr8)
Strain sp. nov.
Complete Yes
Sequencing centre (01-MAR-2011) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA
(16-AUG-2009) Rattei T., Genome Oriented Bioinformatics, Technische Universitaet Muenchen, Am Forum 1, Bavaria, D-85354
Sequencing quality Level 6: Finished
Sequencing depth NA
Sequencing method Sanger, 454
Isolation site human neonatal meningitis, blood culture
Isolation country Switzerland
Number of replicons 4
Gram staining properties Negative
Shape Bacilli
Mobility Yes
Flagellar presence Yes
Number of membranes 2
Oxygen requirements Facultative
Optimal temperature NA
Temperature range NA
Habitat HostAssociated
Biotic relationship NA
Host name Homo sapiens
Cell arrangement NA
Sporulation NA
Metabolism NA
Energy source NA
Diseases NA
Pathogenicity Yes