Streptococcus dysgalactiae subsp. equisimilis GGS_124

Streptococcus_dysgalactiae
Names Streptococcus dysgalactiae subsp. equisimilis GGS_124
Accession numbers NC_012891
Background Streptococcus dysgalactiae (SD) is one of several Lancefield group C, G, and L streptococci falling within the pyogenic group of Streptococcus. It has been divided into 2 subspecies, S.dysgalactiae subsp. dysgalactiae (SDD) which is pathogenic for animals and S. dysgalactiae subsp. equisimilis (SDE) which is both a human commensal organism and a human pathogen. SDE was primarily regarded as a human commensal organism but is now recognized as an increasingly important human pathogen, which can cause a wide spectrum of human diseases, including cellulitis, peritonitis, septic arthritis, pneumonia, endocarditis, acute pharyngitis, bacteremia, and toxic shock syndrome. It can also cause disease in animals. Strain D166B is a Lancefield group G SDE, collected in 1939 from a blister of a child with epidermolysis bullosa, an inherited skin disorder that causes blistering in response to minor injury. Comparison of 2 SDE genomes with a draft SDD genome indicated the 2 subspecies are very similar with only 12-16% unique genes. Most differences lie in the virulence loci (adapted from PMID 15236673). (EBI Integr8)
Taxonomy
Kingdom:Bacteria
Phylum:Firmicutes
Class:Bacilli
Order:Lactobacillales
Family:Streptococcaceae
Genus:Streptococcus
Species:dysgalactiae
Strain GGS_124
Complete Yes
Sequencing centre (01-JUL-2009) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA
(03-DEC-2008) Contact:Tohru Akiyama International Medical Center of Japan, Department of Infectious Diseases
Toyama 1-21-1,
Sequencing quality Level 6: Finished
Sequencing depth NA
Sequencing method Sanger
Isolation site patients with STSS
Isolation country NA
Number of replicons 1
Gram staining properties Positive
Shape Cocci
Mobility No
Flagellar presence No
Number of membranes 1
Oxygen requirements Facultative
Optimal temperature NA
Temperature range Mesophilic
Habitat HostAssociated
Biotic relationship Free living
Host name Homo sapiens
Cell arrangement Chains, Singles
Sporulation Nonsporulating
Metabolism NA
Energy source NA
Diseases Endocarditis. septicemia, meningitis
Pathogenicity Yes