Methylobacterium extorquens AM1

Names Methylobacterium extorquens AM1
Accession numbers NC_012807, NC_012808, NC_012809, NC_012810, NC_012811
Background Methylobacterium extorquens (strain ATCC 14718 / DSM 1338 / AM1) is a pink-pigmented facultative methylotrophs Gram-negative bacterium isolated in 1960 in Oxford, as an airborne contaminant growing on methylamine. It was used as a workhorse to characterize the serine cycle for assimilation of the C1-unit of methylene tetrahydrofolate, a central intermediate in methylotrophic metabolism, and more recently the ethylmalonyl-CoA pathway for glyoxylate regeneration. The common trait of all Methylobacterium species is the ability to grow on one or several reduced one carbon (C1) compounds other than methane, most prominently methanol. M. extorquens contains large sets of insertion elements, many of them strain-specific, suggesting an important potential for genomic plasticity. Most of the genomic determinants associated with methylotrophy are nearly identical in all strains with exceptions that illustrate the metabolic and genomic versatility of Methylobacterium species. M.extorquens (strain ATCC 14718 / DSM 1338 / AM1) possesses a unique methylamine utilization (mau) gene cluster, indicating that strain DSM 5838 / DM4 employs an alternative system for growth with methylamine. The mau clusters represent a chromosomal genomic island and is flanked by mobile elements.(Adaptated from PMID: 19440302). (EBI Integr8)
Taxonomy
Kingdom:Bacteria
Phylum:Proteobacteria
Class:Alphaproteobacteria
Order:Rhizobiales
Family:Methylobacteriaceae
Genus:Methylobacterium
Species:extorquens
Strain AM1
Complete Yes
Sequencing centre (13-MAR-2009) Genome Center, University of Washington, Box 352145, Seattle, WA 98195, USA
(17-JUN-2009) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA
Sequencing quality Level 6: Finished
Sequencing depth NA
Sequencing method Sanger
Isolation site Air
Isolation country NA
Number of replicons 5
Gram staining properties Negative
Shape Bacilli
Mobility Yes
Flagellar presence No
Number of membranes 2
Oxygen requirements Facultative
Optimal temperature 25.0
Temperature range Mesophilic
Habitat Multiple
Biotic relationship Free living
Host name NA
Cell arrangement Pairs, Singles
Sporulation Nonsporulating
Metabolism NA
Energy source Methylotroph
Diseases NA
Pathogenicity No