Wolbachia sp. wRi

Wolbachia_sp.
Names Wolbachia sp. wRi
Accession numbers NC_012416
Background Wolbachia strain TRS is the obligate endosymbiont of the nematode Brugia malayi and is required for fertility and survival of the worm. Brugia malayi as well as Wuchereria bancrofti cause lymphatic filariasis, a disease that affects 120 million people, a third of whom show disfigurement. In nematodes, Wolbachia is located in the lateral chords in both sexes and are also localized in oocytes. The bacterium seems to be present in 100% of individuals within a population, when a species contains them. As they appear to be essential to the worm survival, they represent potential therapeutic targets for filariasis control. Some antibiotics show inhibitory effects on parasitic nematode development and fertility. No antibiotic effects are observed in nematodes that do not harbor Wolbachia. Wolbachia play a role in the host immunological response to filarial parasite invasion. Infection by filarial parasites results in the production of antibodies directed toward parasite- and Wolbachia-specific antigens.(From http://www.expasy.org/sprot/hamap/WOLTR.html) (BacMap)
Taxonomy
Kingdom:Bacteria
Phylum:Proteobacteria
Class:Alphaproteobacteria
Order:Rickettsiales
Family:Anaplasmataceae
Genus:Wolbachia
Species:wRi
Strain wRi
Complete Yes
Sequencing centre (21-JAN-2009) Department of Molecular Evolution, Uppsala University, Norbyvagen 18C, Uppsala 75236, Sweden
(25-MAR-2009) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA
Sequencing quality NA
Sequencing depth NA
Sequencing method NA
Isolation site NA
Isolation country NA
Number of replicons 1
Gram staining properties Negative
Shape NA
Mobility No
Flagellar presence No
Number of membranes NA
Oxygen requirements NA
Optimal temperature NA
Temperature range NA
Habitat HostAssociated
Biotic relationship NA
Host name NA
Cell arrangement NA
Sporulation NA
Metabolism NA
Energy source NA
Diseases NA
Pathogenicity No