Streptococcus uberis 0140J
Names | Streptococcus uberis 0140J |
---|---|
Accession numbers | NC_012004 |
Background | Gram-positive nonmotile coccus. Streptococcus uberis is commensal at many body sites and has been isolated from the skin, gut, tonsils and genital tract of asymptomatic cattle. It can infect the bovine mammary gland where it causes mastitis, an inflammatory disease. Infection with S. uberis is one of the major causes of bovine mastitis worldwide and the most common cause in the UK. S.uberis is often detected in feces and can also be isolated from the environment (pasture, bedding materials) populated by cattle. However the organism survives in the environment for less than 4 weeks. It has been placed within the pyogenic cluster, a large grouping containing the human pathogens S.pyogenes, the zoonotic S.agalactiae and a number of animal pathogens occupying diverse ecological niches including S.equi and S.canis.S. uberis strain 0140J represents a typical UK isolate in terms of its ancestry. It is among the most thoroughly characterized strains that is pathogenic for both the lactating and non-lactating bovine mammary gland, environments that are quite different. It encodes a variety of metabolic options useful for benefiting from its various habitats; some of them have probably been acquired by horizontal gene transfer. It encodes a lower number of mobile genetic elements than other pyogenic streptococci (adapted from PubMed 19175920). (HAMAP: STRU0) |
Taxonomy | |
Kingdom: | Bacteria |
Phylum: | Firmicutes |
Class: | Bacilli |
Order: | Lactobacillales |
Family: | Streptococcaceae |
Genus: | Streptococcus |
Species: | uberis |
Strain | 0140J |
Complete | Yes |
Sequencing centre | (10-MAR-2008) Holden M.T.G., Pathogen Genomics, Sanger Institute Wellcome Trust, Wellcome Trust Genome Campus, Hinxton, (29-JAN-2009) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA |
Sequencing quality | Level 6: Finished |
Sequencing depth | NA |
Sequencing method | Sanger |
Isolation site | clinical bovine mastitis case |
Isolation country | NA |
Number of replicons | 1 |
Gram staining properties | Positive |
Shape | Cocci |
Mobility | No |
Flagellar presence | No |
Number of membranes | 1 |
Oxygen requirements | Facultative |
Optimal temperature | 37.0 |
Temperature range | Mesophilic |
Habitat | Multiple |
Biotic relationship | Free living |
Host name | Bovine |
Cell arrangement | Chains, Pairs |
Sporulation | Nonsporulating |
Metabolism | NA |
Energy source | NA |
Diseases | Mastitis |
Pathogenicity | NA |
Glycolysis / Gluconeogenesis
Pentose phosphate pathway
Galactose metabolism
Synthesis and degradation of ketone bodies
Purine metabolism
Pyrimidine metabolism
Alanine, aspartate and glutamate metabolism
Valine, leucine and isoleucine biosynthesis
Lysine biosynthesis
Selenocompound metabolism
D-Glutamine and D-glutamate metabolism
D-Alanine metabolism
Streptomycin biosynthesis
Peptidoglycan biosynthesis
Pyruvate metabolism
Butanoate metabolism
One carbon pool by folate
Pantothenate and CoA biosynthesis
Folate biosynthesis
Terpenoid backbone biosynthesis
Aminoacyl-tRNA biosynthesis
Pentose phosphate pathway
Galactose metabolism
Synthesis and degradation of ketone bodies
Purine metabolism
Pyrimidine metabolism
Alanine, aspartate and glutamate metabolism
Valine, leucine and isoleucine biosynthesis
Lysine biosynthesis
Selenocompound metabolism
D-Glutamine and D-glutamate metabolism
D-Alanine metabolism
Streptomycin biosynthesis
Peptidoglycan biosynthesis
Pyruvate metabolism
Butanoate metabolism
One carbon pool by folate
Pantothenate and CoA biosynthesis
Folate biosynthesis
Terpenoid backbone biosynthesis
Aminoacyl-tRNA biosynthesis