Acidithiobacillus ferrooxidans ATCC 23270
Names | Acidithiobacillus ferrooxidans ATCC 23270 |
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Accession numbers | NC_011761 |
Background | Acidithiobacillus ferrooxidans (strain ATCC 23270 / DSM 14882 / NCIB 8455) is a facultative anaerobic, chemolithoautotrophic, Gram-negative proteobacterium that thrives optimally at 30 degrees Celsius and pH 2, but can grow at pH 1 or lower. It is abundant in areas of high sulfur content and in natural environments associated with pyritic ore bodies, coal deposits, and their acidified drainages.A. ferrooxidans is one of the few microorganisms known to gain energy by the oxidation of ferrous iron in acidic environments, using the low pH of its natural environment to generate reverse electron flow from Fe(II) to NADH. It can also obtain energy by the oxidation of reduced sulfur compounds, hydrogen, and formate. A. ferrooxidans, which has several D-ribulose-1,5-bisphosphate carboxylase/oxygenase (RuBisCO), fixes CO2 via the Calvin cycle using energy and reducing power derived from the oxidation of iron or sulfur. It can meet its nitrogen needs by either nitrogen fixation or ammonia assimilation.The microorganism makes an important contribution to the biogeochemical cycling of metals in the environment and has the potential to assist in the bioremediation of contaminated sites and for the recovery of important metals such as gold, uranium, and copper from low grade ore by its ability to oxidize and reduce metals. It is for this reason that A. ferrooxidans is used in a bacterial consortium, along with the organism Leptospirillum ferrooxidans by mining companies for extraction of metals. For example, it is used to recover copper via a process known as bioleaching or biomining. Bioleaching of copper ores is a two-step process: first, the biological oxidation of Fe(II) to produce Fe(III); second, the chemical oxidation of Cu(I) to the more soluble Cu(II) by Fe(III) which is reduced to Fe(II) in the process. A. ferrooxidans plays a key role by reoxidizing the Fe(II) to Fe(III), thus completing the cycle and allowing bioleaching to continue. Another unusual propertie of A. ferrooxidans is its ability to aerobically oxidize solid substrates such as pyrite (FeS2). Since the substrate cannot enter the cell, initial electron removal must take place either within the outer cell membrane or completely outside the cell via extracellular polymeric substances. (HAMAP: ACIF2) |
Taxonomy | |
Kingdom: | Bacteria |
Phylum: | Proteobacteria |
Class: | Gammaproteobacteria |
Order: | Acidithiobacillales |
Family: | Acidithiobacillaceae |
Genus: | Acidithiobacillus |
Species: | ferrooxidans |
Strain | ATCC 23270 |
Complete | Yes |
Sequencing centre | (19-DEC-2008) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA (30-OCT-2008) The J. Craig Venter Institute, Rockville, MD, USA |
Sequencing quality | Level 6: Finished |
Sequencing depth | NA |
Sequencing method | NA |
Isolation site | derived from the type strain DSM 2705 |
Isolation country | NA |
Number of replicons | 1 |
Gram staining properties | Negative |
Shape | Bacilli |
Mobility | Yes |
Flagellar presence | No |
Number of membranes | 2 |
Oxygen requirements | Facultative |
Optimal temperature | 30.0 |
Temperature range | Mesophilic |
Habitat | Multiple |
Biotic relationship | Free living |
Host name | NA |
Cell arrangement | NA |
Sporulation | Nonsporulating |
Metabolism | Iron oxidizer |
Energy source | Obligate chemoautolithotroph |
Diseases | NA |
Pathogenicity | No |
Glycolysis / Gluconeogenesis
Citrate cycle (TCA cycle)
Pentose phosphate pathway
Purine metabolism
Pyrimidine metabolism
Alanine, aspartate and glutamate metabolism
Cysteine and methionine metabolism
Valine, leucine and isoleucine biosynthesis
Lysine biosynthesis
Histidine metabolism
Phenylalanine, tyrosine and tryptophan biosynthesis
Selenocompound metabolism
D-Glutamine and D-glutamate metabolism
D-Alanine metabolism
Glutathione metabolism
Streptomycin biosynthesis
Lipopolysaccharide biosynthesis
Peptidoglycan biosynthesis
Pyruvate metabolism
C5-Branched dibasic acid metabolism
One carbon pool by folate
Carbon fixation in photosynthetic organisms
Thiamine metabolism
Riboflavin metabolism
Vitamin B6 metabolism
Pantothenate and CoA biosynthesis
Biotin metabolism
Lipoic acid metabolism
Folate biosynthesis
Terpenoid backbone biosynthesis
Sulfur metabolism
Aminoacyl-tRNA biosynthesis
Citrate cycle (TCA cycle)
Pentose phosphate pathway
Purine metabolism
Pyrimidine metabolism
Alanine, aspartate and glutamate metabolism
Cysteine and methionine metabolism
Valine, leucine and isoleucine biosynthesis
Lysine biosynthesis
Histidine metabolism
Phenylalanine, tyrosine and tryptophan biosynthesis
Selenocompound metabolism
D-Glutamine and D-glutamate metabolism
D-Alanine metabolism
Glutathione metabolism
Streptomycin biosynthesis
Lipopolysaccharide biosynthesis
Peptidoglycan biosynthesis
Pyruvate metabolism
C5-Branched dibasic acid metabolism
One carbon pool by folate
Carbon fixation in photosynthetic organisms
Thiamine metabolism
Riboflavin metabolism
Vitamin B6 metabolism
Pantothenate and CoA biosynthesis
Biotin metabolism
Lipoic acid metabolism
Folate biosynthesis
Terpenoid backbone biosynthesis
Sulfur metabolism
Aminoacyl-tRNA biosynthesis