Oligotropha carboxidovorans OM5
Names | Oligotropha carboxidovorans OM5 |
---|---|
Accession numbers | NC_011386, NC_015684, NC_015685, NC_015689 |
Background | Oligotropha carboxidovorans (strain ATCC 49405 / DSM 1227 / OM5) is a chemolithoautotrophic bacterium with the capability to utilize carbon monoxide, carbon dioxide, and hydrogen as an energy source. It was originally isolated from wastewater by enrichment culture studies that were conducted to isolate CO-utilizing bacteria. Originally identified as Pseudomonas carboxidovorans, it was reclassified later as Oligotropha carboxidovorans. No plasmids were found except the megaplasmid pHCG3. The gene for carbon monoxide dehydrogenase, a key enzyme in the utilization of carbon monoxide, is carried on the low-copy-number megaplasmid, which contains also the genes required for chemolithoautotrophic utilization of CO and CO2 (carboxidotrophy), H2 and CO2 (hydrogenotrophy), and CO2 fixation under aerobic conditions. It is also capable of heterotrophic growth under appropriate environmental conditions. O. carboxidovorans is capable of utilizing syngas, a mixture of CO, CO2, and H2 that results from gasification of organic wastes for chemolithoautotrophic growth. Microbial fermentation of this gas mixture could serve as a source for biofuels. The O. carboxidovorans genome sequence will allow future investigations into how it is able to assimilate carbon that is fixed by chemolithoautotrophy into its metabolism, which could benefit the future use of syngas for biofuel production. (EBI Integr8) |
Taxonomy | |
Kingdom: | Bacteria |
Phylum: | Proteobacteria |
Class: | Alphaproteobacteria |
Order: | Rhizobiales |
Family: | Bradyrhizobiaceae |
Genus: | Oligotropha |
Species: | carboxidovorans |
Strain | OM5 |
Complete | Yes |
Sequencing centre | (22-JUN-2011) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA (25-MAY-2011) Goettingen Genomics Laboratory, Georg-August University Goettingen, Institute of Microbiology and |
Sequencing quality | Level 6: Finished |
Sequencing depth | NA |
Sequencing method | 454 |
Isolation site | wastewater enrichment culture |
Isolation country | Germany |
Number of replicons | 4 |
Gram staining properties | Negative |
Shape | Bacilli |
Mobility | Yes |
Flagellar presence | Yes |
Number of membranes | 2 |
Oxygen requirements | Aerobic |
Optimal temperature | NA |
Temperature range | Mesophilic |
Habitat | Multiple |
Biotic relationship | Free living |
Host name | NA |
Cell arrangement | NA |
Sporulation | NA |
Metabolism | NA |
Energy source | Chemolithoautotroph |
Diseases | NA |
Pathogenicity | No |
Glycolysis / Gluconeogenesis
Citrate cycle (TCA cycle)
Pentose phosphate pathway
Fatty acid metabolism
Synthesis and degradation of ketone bodies
Purine metabolism
Pyrimidine metabolism
Alanine, aspartate and glutamate metabolism
Glycine, serine and threonine metabolism
Cysteine and methionine metabolism
Valine, leucine and isoleucine degradation
Valine, leucine and isoleucine biosynthesis
Lysine biosynthesis
Histidine metabolism
Phenylalanine, tyrosine and tryptophan biosynthesis
Selenocompound metabolism
D-Glutamine and D-glutamate metabolism
D-Arginine and D-ornithine metabolism
D-Alanine metabolism
Streptomycin biosynthesis
Lipopolysaccharide biosynthesis
Peptidoglycan biosynthesis
Pyruvate metabolism
Glyoxylate and dicarboxylate metabolism
Propanoate metabolism
Butanoate metabolism
C5-Branched dibasic acid metabolism
One carbon pool by folate
Thiamine metabolism
Riboflavin metabolism
Vitamin B6 metabolism
Pantothenate and CoA biosynthesis
Biotin metabolism
Lipoic acid metabolism
Folate biosynthesis
Terpenoid backbone biosynthesis
Sulfur metabolism
Aminoacyl-tRNA biosynthesis
Citrate cycle (TCA cycle)
Pentose phosphate pathway
Fatty acid metabolism
Synthesis and degradation of ketone bodies
Purine metabolism
Pyrimidine metabolism
Alanine, aspartate and glutamate metabolism
Glycine, serine and threonine metabolism
Cysteine and methionine metabolism
Valine, leucine and isoleucine degradation
Valine, leucine and isoleucine biosynthesis
Lysine biosynthesis
Histidine metabolism
Phenylalanine, tyrosine and tryptophan biosynthesis
Selenocompound metabolism
D-Glutamine and D-glutamate metabolism
D-Arginine and D-ornithine metabolism
D-Alanine metabolism
Streptomycin biosynthesis
Lipopolysaccharide biosynthesis
Peptidoglycan biosynthesis
Pyruvate metabolism
Glyoxylate and dicarboxylate metabolism
Propanoate metabolism
Butanoate metabolism
C5-Branched dibasic acid metabolism
One carbon pool by folate
Thiamine metabolism
Riboflavin metabolism
Vitamin B6 metabolism
Pantothenate and CoA biosynthesis
Biotin metabolism
Lipoic acid metabolism
Folate biosynthesis
Terpenoid backbone biosynthesis
Sulfur metabolism
Aminoacyl-tRNA biosynthesis