Lactobacillus casei str. Zhang

Names Lactobacillus casei str. Zhang
Accession numbers NC_011352, NC_014334
Background Lactobacilli are normal inhabitants of the gastrointestinal tract of man and animals where they are widely considered to exert a number of beneficial roles including immunomodulation, interference with enteric pathogens, and maintenance of a healthy intestinal microflora. Historically, probiotic roles have been ascribed primarily to Lactobacillus acidophilus. The genus Lactobacillus presently comprises more than 50 recognized species of non pathogenic bacteria which in addition to their probiotic effects are useful to human as indispensable agents for the fermentation of foods and feed. Like other lactic acid bacteria, L. casei are acid tolerant, cannot synthesize porphyrins, and possess a strictly fermentative metabolism with lactic acid as the major metabolic end product. Within the genus Lactobacillus, L. casei form part of the facultatively heterofermentative species cluster, which produce lactic acid from hexose sugars via the Embden-Meyerhof pathway and from pentoses by the 6-phosphogluconate/phosphoketolase pathway. L. casei are a remarkably adaptive species, and may be isolated from raw and fermented dairy products, fresh and fermented plant products, and the reproductive and intestinal tracts of humans and other animals. Industrially, L. casei have application as human probiotics (health-promoting live culture), as acid-producing starter cultures for milk fermentation, and as specialty cultures for the intensification and acceleration of flavor development in certain bacterial-ripened cheese varieties (adapted from (HAMAP: LACC3)
Strain Zhang
Complete Yes
Sequencing centre (16-MAY-2008) Department of Animal Science, College of Agriculture and Biology, Shanghai Jiao Tong University, Shanghai,
(16-MAY-2008) Key Laboratory of Dairy Biotechnology and Engineering, Ministry of Education, College of Food Science and
(16-MAY-2008) Key Laboratory of Genome Sciences and Information, Beijing Institute of Genomics, Chinese Academy of
(20-JUL-2010) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA
Sequencing quality Level 6: Finished
Sequencing depth NA
Sequencing method NA
Isolation site dairy products (Emmental cheese)
Isolation country NA
Number of replicons 2
Gram staining properties Positive
Shape Bacilli
Mobility No
Flagellar presence No
Number of membranes 1
Oxygen requirements Facultative
Optimal temperature 30.0
Temperature range Mesophilic
Habitat Multiple
Biotic relationship Free living
Host name Homo sapiens
Cell arrangement Chains
Sporulation NA
Metabolism NA
Energy source NA
Diseases NA
Pathogenicity No