Borrelia recurrentis A1
| Names | Borrelia recurrentis A1 |
|---|---|
| Accession numbers | NC_011244, NC_011246, NC_011252, NC_011253, NC_011255, NC_011258, NC_011260, NC_011263 |
| Background | Relapsing fever (RF) is a disease caused by several spirochetes of the genus Borrelia. Relapsing fever borrelioses are characterized by recurrent febrile episodes and spirochetemia. There are 2 forms; louse-borne relapsing fever (also known as urban or epidemic RF) is caused by Borrelia recurrentis, and is transmitted by the body louse Pediculus humanus humanus. It currently known in Ethiopia. Endemic tick-borne relapsing fever (TBRF) is a zoonotic disease transmitted worldwide by softbody ticks of the genus Ornithodoros. It is caused by at least 15 distinct Borrelia species throughout the world.Borrelia recurrentis strain A1 was isolated from an adult with RF in Ethiopia. RF causes fewer relapses that TBRF but has a higher spontaneous mortality rate despite antibiotics. Previous work suggested that B.recurrentis was very closely related to B.duttonii; the current sequencing project suggests that in fact B.recurrentis should be considered a strain of B.duttonii that is undergoing considerable gene decay. Decay is probably due at least in part to mutated recA and mutS genes in A1. All 6 plasmids in strain A1 have a counterpart in B.duttonii strain Ly (BORDL). (HAMAP: BORRA) |
| Taxonomy | |
| Kingdom: | Bacteria |
| Phylum: | Spirochaetes |
| Class: | Spirochaetes |
| Order: | Spirochaetales |
| Family: | Spirochaetaceae |
| Genus: | Borrelia |
| Species: | recurrentis |
| Strain | A1 |
| Complete | Yes |
| Sequencing centre | (17-MAR-2008) Institut de Biologie structurale et Microbiologie (IBSM), CNRS-Information Genomique et structurale, (17-SEP-2008) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA |
| Sequencing quality | Level 6: Finished |
| Sequencing depth | NA |
| Sequencing method | NA |
| Isolation site | Adult patient with louse-borne relapsing fever in Ethiopia |
| Isolation country | Ethiopia |
| Number of replicons | 8 |
| Gram staining properties | Negative |
| Shape | Spirilla |
| Mobility | No |
| Flagellar presence | Yes |
| Number of membranes | 2 |
| Oxygen requirements | Aerobic |
| Optimal temperature | NA |
| Temperature range | Mesophilic |
| Habitat | HostAssociated |
| Biotic relationship | Free living |
| Host name | Homo sapiens |
| Cell arrangement | Singles |
| Sporulation | Nonsporulating |
| Metabolism | NA |
| Energy source | NA |
| Diseases | Louse-borne relapsing fever |
| Pathogenicity | Yes |