Streptomyces griseus subsp. griseus NBRC 13350
Names | Streptomyces griseus subsp. griseus NBRC 13350 |
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Accession numbers | NC_010572 |
Background | The genus Streptomyces consists of soil and water Gram positive filamentous bacteria well known for their ability to produce complex secondary metabolites including many antibiotics. Additionally they undergo complex multicellular development, with spores germinating to form a branched, multinucleoid substrate mycelium, which then produces an aerial mycelium which septates into uninucleoid spores. Streptomyces is also unusual in having linear chromosomes with terminal inverted repeats with terminal proteins covalently bound to their 5' ends.Streptomycin, the first aminoglycoside antibiotic, was discovered more than 60 years ago, is still used to treat tuberculosis and is produced commercially by S.griseus. Analysis of the genome of strain JCM 4626 / NBRC 13350 indicates the presence of 34 gene clusters or genes for the biosynthesis of known or unknown secondary metabolites. (HAMAP: STRGG) |
Taxonomy | |
Kingdom: | Bacteria |
Phylum: | Actinobacteria |
Class: | Actinobacteria |
Order: | Actinomycetales |
Family: | Streptomycetaceae |
Genus: | Streptomyces |
Species: | griseus |
Strain | NBRC 13350 |
Complete | Yes |
Sequencing centre | (10-APR-2008) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA (23-AUG-2007) Contact:Masahira Hattori Graduate School of Frontier Sciences, The University of Tokyo Kashiwanoha 5-1-5, |
Sequencing quality | Level 6: Finished |
Sequencing depth | NA |
Sequencing method | Sanger |
Isolation site | NA |
Isolation country | NA |
Number of replicons | 1 |
Gram staining properties | Positive |
Shape | Tailed |
Mobility | Yes |
Flagellar presence | No |
Number of membranes | 1 |
Oxygen requirements | Aerobic |
Optimal temperature | 25.0 |
Temperature range | Mesophilic |
Habitat | Multiple |
Biotic relationship | Free living |
Host name | NA |
Cell arrangement | Filaments |
Sporulation | Sporulating |
Metabolism | Streptomycin producer |
Energy source | NA |
Diseases | None |
Pathogenicity | No |
Glycolysis / Gluconeogenesis
Citrate cycle (TCA cycle)
Pentose phosphate pathway
Fatty acid metabolism
Synthesis and degradation of ketone bodies
Purine metabolism
Pyrimidine metabolism
Alanine, aspartate and glutamate metabolism
Glycine, serine and threonine metabolism
Cysteine and methionine metabolism
Valine, leucine and isoleucine degradation
Geraniol degradation
Valine, leucine and isoleucine biosynthesis
Lysine biosynthesis
Penicillin and cephalosporin biosynthesis
Arginine and proline metabolism
Histidine metabolism
Phenylalanine, tyrosine and tryptophan biosynthesis
beta-Alanine metabolism
Taurine and hypotaurine metabolism
Selenocompound metabolism
D-Glutamine and D-glutamate metabolism
D-Arginine and D-ornithine metabolism
D-Alanine metabolism
Starch and sucrose metabolism
Amino sugar and nucleotide sugar metabolism
Streptomycin biosynthesis
Peptidoglycan biosynthesis
Pyruvate metabolism
Glyoxylate and dicarboxylate metabolism
Nitrotoluene degradation
Propanoate metabolism
Butanoate metabolism
C5-Branched dibasic acid metabolism
One carbon pool by folate
Methane metabolism
Thiamine metabolism
Riboflavin metabolism
Vitamin B6 metabolism
Nicotinate and nicotinamide metabolism
Pantothenate and CoA biosynthesis
Biotin metabolism
Lipoic acid metabolism
Folate biosynthesis
Porphyrin and chlorophyll metabolism
Terpenoid backbone biosynthesis
Nitrogen metabolism
Sulfur metabolism
Caprolactam degradation
Aminoacyl-tRNA biosynthesis
Citrate cycle (TCA cycle)
Pentose phosphate pathway
Fatty acid metabolism
Synthesis and degradation of ketone bodies
Purine metabolism
Pyrimidine metabolism
Alanine, aspartate and glutamate metabolism
Glycine, serine and threonine metabolism
Cysteine and methionine metabolism
Valine, leucine and isoleucine degradation
Geraniol degradation
Valine, leucine and isoleucine biosynthesis
Lysine biosynthesis
Penicillin and cephalosporin biosynthesis
Arginine and proline metabolism
Histidine metabolism
Phenylalanine, tyrosine and tryptophan biosynthesis
beta-Alanine metabolism
Taurine and hypotaurine metabolism
Selenocompound metabolism
D-Glutamine and D-glutamate metabolism
D-Arginine and D-ornithine metabolism
D-Alanine metabolism
Starch and sucrose metabolism
Amino sugar and nucleotide sugar metabolism
Streptomycin biosynthesis
Peptidoglycan biosynthesis
Pyruvate metabolism
Glyoxylate and dicarboxylate metabolism
Nitrotoluene degradation
Propanoate metabolism
Butanoate metabolism
C5-Branched dibasic acid metabolism
One carbon pool by folate
Methane metabolism
Thiamine metabolism
Riboflavin metabolism
Vitamin B6 metabolism
Nicotinate and nicotinamide metabolism
Pantothenate and CoA biosynthesis
Biotin metabolism
Lipoic acid metabolism
Folate biosynthesis
Porphyrin and chlorophyll metabolism
Terpenoid backbone biosynthesis
Nitrogen metabolism
Sulfur metabolism
Caprolactam degradation
Aminoacyl-tRNA biosynthesis