Brucella suis ATCC 23445

Names Brucella suis ATCC 23445
Accession numbers NC_010167, NC_010169
Background The genus Brucella is comprised mostly of mammalian pathogens, which due to their low infectious does, aerosol transmission and treatment difficulty are classified as potential bioterrorism agents. Brucellosis is a major infectious disease for both human and animals. Several Brucella species (B.abortus, B.melitensis and B.suis) have been isolated from many different animals. All three Brucella species cause a severe human disease characterized in its acute phase by undulant fever and in its chronic phase by damage of different organs. When the infection is localized to the brain or the heart, it can result in a fatal meningitidis or fatal endocarditis, respectively. Brucellosis is a major problem in the Mediterranean region and parts of Asia, Africa and Latin America. Brucella suis was the first pathogenic organism weaponized by the U.S. military during the 1950s. Although Brucellae contain a large set of flagellar genes, they display a species-specific gene inactivation and consequently are nonmotile. (EBI Integr8)
Strain ATCC 23445
Complete Yes
Sequencing centre (06-DEC-2007) The Pathosystems Resource Integration Center (PATRIC), Virginia Bioinformatics Institute at Virginia
(21-DEC-2007) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA
Sequencing quality Level 6: Finished
Sequencing depth NA
Sequencing method Sanger
Isolation site hare
Isolation country NA
Number of replicons 2
Gram staining properties Negative
Shape Bacilli
Mobility No
Flagellar presence No
Number of membranes 2
Oxygen requirements Aerobic
Optimal temperature 37.0
Temperature range Mesophilic
Habitat HostAssociated
Biotic relationship Free living
Host name Homo sapiens
Cell arrangement Chains, Pairs, Singles
Sporulation Nonsporulating
Metabolism NA
Energy source NA
Diseases Brucellosis, infectious abortions, fever
Pathogenicity Yes