Rickettsia akari str. Hartford
Names | Rickettsia akari str. Hartford |
---|---|
Accession numbers | NC_009881 |
Background | Rickettsia akari is the causative agent of rickettsialpox. The disease was first described in 1946 in residents of the borough of Queens, in New York. Small outbreaks of rickettsialpox occured in several U.S cities, including Boston and Cleveland. About half of the cases occured in New York. To date, most cases have occurred in large metropolitan areas of the northeastern United State. Recently cases of rickettsialpox have been reported in Ukraine and Croatia. Rickettsia akari is transmitted among house mice and to humans by the house mouse mite Liponyssoides sanguineus but isolations have also been made from Korean voles in an area where rickettsialpox has not been reported. The first symptom of rickettsialpox is a papule which appears at the site of the original bite. The papule develops a tiny, fluid-filled vesicle. The vesicle sloughs away, leaving a crusty black scab (eschar) in its place. In about a week, the patient develops a fever, chills, heavy sweating, headache, eye pain (especially when exposed to light), weakness, and achy muscles. The fever rises and falls over the course of about a weak. A bumpy rash spreads across the body. (EBI Integr8) |
Taxonomy | |
Kingdom: | Bacteria |
Phylum: | Proteobacteria |
Class: | Alphaproteobacteria |
Order: | Rickettsiales |
Family: | Rickettsiaceae |
Genus: | Rickettsia |
Species: | akari |
Strain | Hartford |
Complete | Yes |
Sequencing centre | (01-AUG-2000) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA (27-SEP-2007) Neurogenomics Research Lab, University of Iowa, 200 B EMRB, Iowa City, IA 52242, USA |
Sequencing quality | Level 6: Finished |
Sequencing depth | NA |
Sequencing method | Sanger |
Isolation site | NA |
Isolation country | NA |
Number of replicons | 1 |
Gram staining properties | Negative |
Shape | Bacilli |
Mobility | No |
Flagellar presence | No |
Number of membranes | 2 |
Oxygen requirements | Aerobic |
Optimal temperature | NA |
Temperature range | Mesophilic |
Habitat | HostAssociated |
Biotic relationship | Symbiotic |
Host name | Homo sapiens |
Cell arrangement | NA |
Sporulation | Nonsporulating |
Metabolism | NA |
Energy source | NA |
Diseases | Rickettsialpox |
Pathogenicity | Yes |
Citrate cycle (TCA cycle)
Synthesis and degradation of ketone bodies
Pyrimidine metabolism
D-Alanine metabolism
Lipopolysaccharide biosynthesis
Peptidoglycan biosynthesis
One carbon pool by folate
Lipoic acid metabolism
Folate biosynthesis
Aminoacyl-tRNA biosynthesis
Synthesis and degradation of ketone bodies
Pyrimidine metabolism
D-Alanine metabolism
Lipopolysaccharide biosynthesis
Peptidoglycan biosynthesis
One carbon pool by folate
Lipoic acid metabolism
Folate biosynthesis
Aminoacyl-tRNA biosynthesis