Staphylococcus aureus subsp. aureus JH1

Staphylococcus_aureus
Names Staphylococcus aureus subsp. aureus JH1
Accession numbers NC_009619, NC_009632
Background Staphylococcus aureus subsp. aureus strain JH1. A series of isogenic methicillin-resistant (MRSA) strains were isolated from a patient undergoing vancomycin treatment. The chronologically earliest strain (JH1) was vancomycin sensitive, while the latest strain (JH9) exhibited increased vancomycin resistance (VISA-type vancomycin resistance). Comparison of these two strains will enable understanding of the evolutionary events that occur under the selective pressure of the presence of antibiotics as well as help explain the genetic basis for vancomycin resistance. (NCBI BioProject: bp_list[1])
Taxonomy
Kingdom:Bacteria
Phylum:Firmicutes
Class:Bacilli
Order:Bacillales
Family:Staphylococcaceae
Genus:Staphylococcus
Species:aureus
Strain JH1
Complete Yes
Sequencing centre (03-JUL-2007) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA
(20-JUN-2007) US DOE Joint Genome Institute, 2800 Mitchell Drive B100, Walnut Creek, CA 94598-1698, USA
Sequencing quality Level 6: Finished
Sequencing depth NA
Sequencing method NA
Isolation site Pus of a Japanese male baby with a surgical wound infection that did not respond to vancomycin in 1997
Isolation country Japan
Number of replicons 2
Gram staining properties Positive
Shape Cocci
Mobility No
Flagellar presence No
Number of membranes 1
Oxygen requirements Facultative
Optimal temperature 30.0
Temperature range Mesophilic
Habitat HostAssociated
Biotic relationship Free living
Host name Homo sapiens
Cell arrangement Clusters, Singles
Sporulation Nonsporulating
Metabolism NA
Energy source NA
Diseases Toxic-shock syndrome and staphylococcal scarlet fever
Pathogenicity NA