Methanobrevibacter smithii ATCC 35061

Names | Methanobrevibacter smithii ATCC 35061 |
---|---|
Accession numbers | NC_009515 |
Background | Methanobrevibacter smithii (strain ATCC 35061 / DSM 861) is a methanogenic Euryarchaeote which is the dominant archeon in the human gut ecosystem and makes up 10% of all anaerobes in the colons of healthy adults. Studies in gnotobiotic mice indicate that M. smithii affects the specificity and efficiency of bacterial digestion of dietary polysaccharide, thereby influencing host calorie harvest and adiposity. Comparison of the gut microbial communities of genetically obese and lean mice has shown that the former contain an enhanced representation of genes involved in polysaccharide degradation, possess more archaea and exhibit a greater capacity to promote adiposity when transplanted in germ-free recipients. These findings suggest that M. smithii may be a therapeutic target for reducing energy harvest in obese human. (HAMAP: METS3) |
Taxonomy | |
Kingdom: | Archaea |
Phylum: | Euryarchaeota |
Class: | Methanobacteria |
Order: | Methanobacteriales |
Family: | Methanobacteriaceae |
Genus: | Methanobrevibacter |
Species: | smithii |
Strain | NA |
Complete | Yes |
Sequencing centre | (06-JUN-2007) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA (13-APR-2007) Center for Genome Sciences, Washington University, 4444 Forest Park, Saint Louis, MO 63108, USA |
Sequencing quality | Level 6: Finished |
Sequencing depth | NA |
Sequencing method | Sanger |
Isolation site | Sewage digester in Gainesville Florida |
Isolation country | USA |
Number of replicons | 1 |
Gram staining properties | Positive |
Shape | Bacilli |
Mobility | No |
Flagellar presence | NA |
Number of membranes | 1 |
Oxygen requirements | Anaerobic |
Optimal temperature | 37.0 |
Temperature range | Mesophilic |
Habitat | Multiple |
Biotic relationship | Free living |
Host name | NA |
Cell arrangement | Chains, Pairs |
Sporulation | NA |
Metabolism | Methanogen |
Energy source | Lithotroph |
Diseases | NA |
Pathogenicity | No |
Citrate cycle (TCA cycle)
Pyrimidine metabolism
Alanine, aspartate and glutamate metabolism
Valine, leucine and isoleucine biosynthesis
Histidine metabolism
Phenylalanine, tyrosine and tryptophan biosynthesis
Streptomycin biosynthesis
C5-Branched dibasic acid metabolism
Methane metabolism
Thiamine metabolism
Riboflavin metabolism
Pantothenate and CoA biosynthesis
Porphyrin and chlorophyll metabolism
Aminoacyl-tRNA biosynthesis
Pyrimidine metabolism
Alanine, aspartate and glutamate metabolism
Valine, leucine and isoleucine biosynthesis
Histidine metabolism
Phenylalanine, tyrosine and tryptophan biosynthesis
Streptomycin biosynthesis
C5-Branched dibasic acid metabolism
Methane metabolism
Thiamine metabolism
Riboflavin metabolism
Pantothenate and CoA biosynthesis
Porphyrin and chlorophyll metabolism
Aminoacyl-tRNA biosynthesis