Methanobrevibacter smithii ATCC 35061

Methanobrevibacter_smithii
Names Methanobrevibacter smithii ATCC 35061
Accession numbers NC_009515
Background Methanobrevibacter smithii (strain ATCC 35061 / DSM 861) is a methanogenic Euryarchaeote which is the dominant archeon in the human gut ecosystem and makes up 10% of all anaerobes in the colons of healthy adults. Studies in gnotobiotic mice indicate that M. smithii affects the specificity and efficiency of bacterial digestion of dietary polysaccharide, thereby influencing host calorie harvest and adiposity. Comparison of the gut microbial communities of genetically obese and lean mice has shown that the former contain an enhanced representation of genes involved in polysaccharide degradation, possess more archaea and exhibit a greater capacity to promote adiposity when transplanted in germ-free recipients. These findings suggest that M. smithii may be a therapeutic target for reducing energy harvest in obese human. (HAMAP: METS3)
Taxonomy
Kingdom:Archaea
Phylum:Euryarchaeota
Class:Methanobacteria
Order:Methanobacteriales
Family:Methanobacteriaceae
Genus:Methanobrevibacter
Species:smithii
Strain NA
Complete Yes
Sequencing centre (06-JUN-2007) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA
(13-APR-2007) Center for Genome Sciences, Washington University, 4444 Forest Park, Saint Louis, MO 63108, USA
Sequencing quality Level 6: Finished
Sequencing depth NA
Sequencing method Sanger
Isolation site Sewage digester in Gainesville Florida
Isolation country USA
Number of replicons 1
Gram staining properties Positive
Shape Bacilli
Mobility No
Flagellar presence NA
Number of membranes 1
Oxygen requirements Anaerobic
Optimal temperature 37.0
Temperature range Mesophilic
Habitat Multiple
Biotic relationship Free living
Host name NA
Cell arrangement Chains, Pairs
Sporulation NA
Metabolism Methanogen
Energy source Lithotroph
Diseases NA
Pathogenicity No