Staphylococcus aureus subsp. aureus JH9

Names Staphylococcus aureus subsp. aureus JH9
Accession numbers NC_009477, NC_009487
Background Staphylococcus aureus subsp. aureus strain JH9. A series of isogenic methicillin-resistant (MRSA) strains were isolated from a patient undergoing vancomycin treatment. The chronologically earliest strain (JH1) was vancomycin sensitive, while the latest strain (JH9) exhibited increased vancomycin resistance (VISA-type vancomycin resistance). Comparison of these two strains will enable understanding of the evolutionary events that occur under the selective pressure of the presence of antibiotics as well as help explain the genetic basis for vancomycin resistance. (NCBI BioProject: bp_list[1])
Strain JH9
Complete Yes
Sequencing centre (14-MAY-2007) US DOE Joint Genome Institute, 2800 Mitchell Drive B100, Walnut Creek, CA 94598-1698, USA
(23-MAY-2007) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA
Sequencing quality Level 6: Finished
Sequencing depth NA
Sequencing method NA
Isolation site Pus of a Japanese male baby with a surgical wound infection that did not respond to vancomycin in 1997
Isolation country Japan
Number of replicons 2
Gram staining properties Positive
Shape Cocci
Mobility No
Flagellar presence No
Number of membranes 1
Oxygen requirements Facultative
Optimal temperature 30.0
Temperature range Mesophilic
Habitat HostAssociated
Biotic relationship Free living
Host name Homo sapiens
Cell arrangement Clusters, Singles
Sporulation Nonsporulating
Metabolism NA
Energy source NA
Diseases Toxic-shock syndrome and staphylococcal scarlet fever
Pathogenicity NA