Streptococcus suis 98HAH33

Streptococcus_suis
Names Streptococcus suis 98HAH33
Accession numbers NC_009443
Background Streptococcus suis is a major porcine pathogen in many countries. It causes serious zoonotic diseases (diseases which can be transmitted naturally between animals and humans) such as meningitis, septicaemia, endocarditis, arthritis, and septic shock in both pigs and human beings, and mortality is high. There are 35 serotypes of S.suis, of which serotype SS2 is the most prevalent. Two recent large-scale outbreaks of streptococcal toxic shock syndrome (STSS) in China were caused by SS2 (in 1998 and 2005). Two highly virulent isolates from fatal cases of STSS, 98HAH33 from the 1998 outbreak and 05ZYH33 from the 2005 outbreak were sequenced and found to contain a novel 89 kb pathogenicity island not detected in other S.suis isolates. The pathogenicity island has probably been acquired by horizontal gene transfer. This might partially explain the virulence of these strains. (EBI Integr8)
Taxonomy
Kingdom:Bacteria
Phylum:Firmicutes
Class:Bacilli
Order:Lactobacillales
Family:Streptococcaceae
Genus:Streptococcus
Species:suis
Strain 98HAH33
Complete Yes
Sequencing centre (08-MAY-2007) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA
(27-JUN-2006) Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing 101300, China
Sequencing quality Level 6: Finished
Sequencing depth NA
Sequencing method NA
Isolation site Chinese virulent strain isolated from fatal cases of STSS in 1998
Isolation country China
Number of replicons 1
Gram staining properties Positive
Shape Cocci
Mobility No
Flagellar presence No
Number of membranes 1
Oxygen requirements Facultative
Optimal temperature 37.0
Temperature range Mesophilic
Habitat Specialized
Biotic relationship Free living
Host name Homo sapiens
Cell arrangement Chains, Pairs, Singles
Sporulation Nonsporulating
Metabolism NA
Energy source NA
Diseases Meningitis, endocarditis, septicemia and arthritis
Pathogenicity Yes