Streptococcus suis 05ZYH33
Names | Streptococcus suis 05ZYH33 |
---|---|
Accession numbers | NC_009442 |
Background | Streptococcus suis is a major porcine pathogen in many countries. It causes serious zoonotic diseases (diseases which can be transmitted naturally between animals and humans) such as meningitis, septicaemia, endocarditis, arthritis, and septic shock in both pigs and human beings, and mortality is high. There are 35 serotypes of S.suis, of which serotype SS2 is the most prevalent. Two recent large-scale outbreaks of streptococcal toxic shock syndrome (STSS) in China were caused by SS2 (in 1998 and 2005). Two highly virulent isolates from fatal cases of STSS, 98HAH33 from the 1998 outbreak and 05ZYH33 from the 2005 outbreak were sequenced and found to contain a novel 89 kb pathogenicity island not detected in other S.suis isolates. The pathogenicity island has probably been acquired by horizontal gene transfer. This might partially explain the virulence of these strains. (HAMAP: STRSY) |
Taxonomy | |
Kingdom: | Bacteria |
Phylum: | Firmicutes |
Class: | Bacilli |
Order: | Lactobacillales |
Family: | Streptococcaceae |
Genus: | Streptococcus |
Species: | suis |
Strain | 05ZYH33 |
Complete | Yes |
Sequencing centre | (08-MAY-2007) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA (27-JUN-2006) Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing 101300, China |
Sequencing quality | Level 6: Finished |
Sequencing depth | NA |
Sequencing method | NA |
Isolation site | Chinese virulent strain isolated from fatal cases of STSS in 2005 |
Isolation country | China |
Number of replicons | 1 |
Gram staining properties | Positive |
Shape | Cocci |
Mobility | No |
Flagellar presence | No |
Number of membranes | 1 |
Oxygen requirements | Facultative |
Optimal temperature | 37.0 |
Temperature range | Mesophilic |
Habitat | Multiple |
Biotic relationship | Free living |
Host name | Homo sapiens |
Cell arrangement | Chains, Pairs, Singles |
Sporulation | Nonsporulating |
Metabolism | NA |
Energy source | NA |
Diseases | Meningitis, endocarditis, septicemia and arthritis |
Pathogenicity | Yes |
Glycolysis / Gluconeogenesis
Citrate cycle (TCA cycle)
Pentose phosphate pathway
Galactose metabolism
Synthesis and degradation of ketone bodies
Purine metabolism
Pyrimidine metabolism
Alanine, aspartate and glutamate metabolism
Cysteine and methionine metabolism
Valine, leucine and isoleucine biosynthesis
Lysine biosynthesis
Selenocompound metabolism
D-Glutamine and D-glutamate metabolism
D-Alanine metabolism
Amino sugar and nucleotide sugar metabolism
Streptomycin biosynthesis
Peptidoglycan biosynthesis
Pyruvate metabolism
C5-Branched dibasic acid metabolism
One carbon pool by folate
Thiamine metabolism
Pantothenate and CoA biosynthesis
Folate biosynthesis
Terpenoid backbone biosynthesis
Aminoacyl-tRNA biosynthesis
Citrate cycle (TCA cycle)
Pentose phosphate pathway
Galactose metabolism
Synthesis and degradation of ketone bodies
Purine metabolism
Pyrimidine metabolism
Alanine, aspartate and glutamate metabolism
Cysteine and methionine metabolism
Valine, leucine and isoleucine biosynthesis
Lysine biosynthesis
Selenocompound metabolism
D-Glutamine and D-glutamate metabolism
D-Alanine metabolism
Amino sugar and nucleotide sugar metabolism
Streptomycin biosynthesis
Peptidoglycan biosynthesis
Pyruvate metabolism
C5-Branched dibasic acid metabolism
One carbon pool by folate
Thiamine metabolism
Pantothenate and CoA biosynthesis
Folate biosynthesis
Terpenoid backbone biosynthesis
Aminoacyl-tRNA biosynthesis