Yersinia enterocolitica subsp. enterocolitica 8081

Names Yersinia enterocolitica subsp. enterocolitica 8081
Accession numbers NC_008791, NC_008800
Background Yersinia enterocolitica is a mammalian gastrointestinal pathogen composed of six biotypes. The biotypes group into three types of pathogen; mouse nonpathogens (biotype 1A), weak mouse pathogens (biotypes 2-5) and a mouse-lethal group (biotype 1B), of which this strain is a member. Biotype 1B is a primarily New World strain. Y.enterocolitica and Y.pseudotuberculosis are thought to have diverged in the last 200 million years, while it has been proposed that Y.pestis (the causative agent of plague) evolved from Y.pseudotuberculosis 1,500-20,000 years ago. Y.pseudotuberculosis and Y.pestis cause more severe clinical symptoms than Y.enterocolitica. The availability of representatives of all three Yersinia species has allowed comparison of gene loss and acquisitions since they diverged. It seems that despite both being enteric pathogens, Y.enterocolitica and Y.pseudotuberculosis occupy different niches as seen by differential losses of presumably adaptive functions such as cellulose biosynthetic genes (present only in Y. enterocolitica) and osmoregulated periplasmic glucan biosynthetic pathway (probably not succinylated in Y.pseudotuberculosis). Like all Yersinia, Y.enterocolitica has an approximately 70 kb virulence plasmid. (EBI Integr8)
Strain 8081
Complete Yes
Sequencing centre (19-JAN-2007) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA
(30-JUN-2006) Thomson N.R., Pathogen Sequencing Unit, The Wellcome Trust Sanger Institute, Genome Campus, Hinxton, Cambridge,
Sequencing quality Level 6: Finished
Sequencing depth NA
Sequencing method Sanger
Isolation site human septicaemia isolate
Isolation country NA
Number of replicons 2
Gram staining properties Negative
Shape Bacilli
Mobility Yes
Flagellar presence Yes
Number of membranes 2
Oxygen requirements Facultative
Optimal temperature 28.0
Temperature range Mesophilic
Habitat Multiple
Biotic relationship Free living
Host name Homo sapiens
Cell arrangement Singles
Sporulation Nonsporulating
Metabolism NA
Energy source Heterotroph
Diseases Gastroenteritis
Pathogenicity Yes