Bartonella bacilliformis KC583
Names | Bartonella bacilliformis KC583 |
---|---|
Accession numbers | NC_008783 |
Background | Bartonella bacilliformis is the causative agent of bartonellosis (also known as Carrion's disease), a biphasic disease endemic to Andean valleys in Peru, Columbia and Ecuador. It is transmitted by the sandfly Phlebotomus verrucarum which is limited to these areas. The bacterium was first isolated in 1909 by the Peruvian physician Albert Barton. Bartonellosis is usually characterized by two distinctive stages: a sudden (acute), potentially life-threatening illness associated with high fever and decreased levels of circulating red blood cells (i.e., hemolytic anemia) called Oroya fever. Mortality rates of up to 40-80% in untreated patients are reported. The second phase, which can take between 2 weeks to several years to manifest is characterized by a chronic, benign skin (cutaneous) eruption consisting of raised, reddish-purple nodules on the head and extremities (called Verruga peruana). (EBI Integr8) |
Taxonomy | |
Kingdom: | Bacteria |
Phylum: | Proteobacteria |
Class: | Alphaproteobacteria |
Order: | Rhizobiales |
Family: | Bartonellaceae |
Genus: | Bartonella |
Species: | bacilliformis |
Strain | KC583 |
Complete | Yes |
Sequencing centre | (10-JAN-2007) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA (18-DEC-2006) The Institute for Genomic Research, 9712 Medical Center Dr, Rockville, MD 20850, USA |
Sequencing quality | Level 6: Finished |
Sequencing depth | NA |
Sequencing method | NA |
Isolation site | NA |
Isolation country | NA |
Number of replicons | 1 |
Gram staining properties | Negative |
Shape | Bacilli |
Mobility | No |
Flagellar presence | Yes |
Number of membranes | 2 |
Oxygen requirements | Aerobic |
Optimal temperature | 28.0 |
Temperature range | Mesophilic |
Habitat | HostAssociated |
Biotic relationship | Symbiotic |
Host name | Homo sapiens |
Cell arrangement | NA |
Sporulation | Nonsporulating |
Metabolism | NA |
Energy source | NA |
Diseases | Carrion's disease, Oroya fever |
Pathogenicity | Yes |
Glycolysis / Gluconeogenesis
Citrate cycle (TCA cycle)
Pyrimidine metabolism
Alanine, aspartate and glutamate metabolism
Valine, leucine and isoleucine biosynthesis
Lysine biosynthesis
D-Glutamine and D-glutamate metabolism
D-Alanine metabolism
Lipopolysaccharide biosynthesis
Peptidoglycan biosynthesis
One carbon pool by folate
Thiamine metabolism
Riboflavin metabolism
Vitamin B6 metabolism
Pantothenate and CoA biosynthesis
Lipoic acid metabolism
Folate biosynthesis
Terpenoid backbone biosynthesis
Aminoacyl-tRNA biosynthesis
Citrate cycle (TCA cycle)
Pyrimidine metabolism
Alanine, aspartate and glutamate metabolism
Valine, leucine and isoleucine biosynthesis
Lysine biosynthesis
D-Glutamine and D-glutamate metabolism
D-Alanine metabolism
Lipopolysaccharide biosynthesis
Peptidoglycan biosynthesis
One carbon pool by folate
Thiamine metabolism
Riboflavin metabolism
Vitamin B6 metabolism
Pantothenate and CoA biosynthesis
Lipoic acid metabolism
Folate biosynthesis
Terpenoid backbone biosynthesis
Aminoacyl-tRNA biosynthesis