Bartonella bacilliformis KC583

Names Bartonella bacilliformis KC583
Accession numbers NC_008783
Background Bartonella bacilliformis is the causative agent of bartonellosis (also known as Carrion's disease), a biphasic disease endemic to Andean valleys in Peru, Columbia and Ecuador. It is transmitted by the sandfly Phlebotomus verrucarum which is limited to these areas. The bacterium was first isolated in 1909 by the Peruvian physician Albert Barton. Bartonellosis is usually characterized by two distinctive stages: a sudden (acute), potentially life-threatening illness associated with high fever and decreased levels of circulating red blood cells (i.e., hemolytic anemia) called Oroya fever. Mortality rates of up to 40-80% in untreated patients are reported. The second phase, which can take between 2 weeks to several years to manifest is characterized by a chronic, benign skin (cutaneous) eruption consisting of raised, reddish-purple nodules on the head and extremities (called Verruga peruana). (EBI Integr8)
Strain KC583
Complete Yes
Sequencing centre (10-JAN-2007) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA
(18-DEC-2006) The Institute for Genomic Research, 9712 Medical Center Dr, Rockville, MD 20850, USA
Sequencing quality Level 6: Finished
Sequencing depth NA
Sequencing method NA
Isolation site NA
Isolation country NA
Number of replicons 1
Gram staining properties Negative
Shape Bacilli
Mobility No
Flagellar presence Yes
Number of membranes 2
Oxygen requirements Aerobic
Optimal temperature 28.0
Temperature range Mesophilic
Habitat HostAssociated
Biotic relationship Symbiotic
Host name Homo sapiens
Cell arrangement NA
Sporulation Nonsporulating
Metabolism NA
Energy source NA
Diseases Carrion's disease, Oroya fever
Pathogenicity Yes