Mycobacterium sp. KMS

Names Mycobacterium sp. KMS
Accession numbers NC_008703, NC_008704, NC_008705
Background Mycobacteria belong to the order Actinomycetales that are Gram-positive, acid-fast, pleomorphic, non-motile rods characterized by distinctive cell surface mycolic acid derivatives. They are obligate aerobes. This isolate belongs to a fast-growing group and actually has a coccus morphology, whereas members of the slow-growing group of Mycobacteria are notorious for causing human and animal diseases.Mycobacterium KMS was isolated from soil in Libby, Montana, USA, the site of a former lumber and plywood mill. The soil is contaminated by polycyclic aromatic hydrocarbons (PAH), and KMS is one of several indigenous mycobacteria isolated from this site that are able to degrade high molecular weight PAH including pyrene, however this isolate cannot degrade benzo(a)pyrene. Other Mycobacteria from this site include strain MCS (MYCSS) and strain JLS (MYCSJ). Strain KMSmineralizes small- and large-ring PAHs, in contrast to other PAH-degrading microbes and thus offers possibilities for bioremediation of PAHs. The genome sequence of the Mycobacterium isolate KMS will permit comparisons with the genomes of pathogenic isolates, as well as an understanding of the pathway for PAH degradation and survival mechanisms in polluted conditions (adapted from (HAMAP: MYCSK)
Strain KMS
Complete Yes
Sequencing centre (18-DEC-2006) US DOE Joint Genome Institute, 2800 Mitchell Drive B100, Walnut Creek, CA 94598-1698, USA
(22-DEC-2006) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA
Sequencing quality Level 6: Finished
Sequencing depth NA
Sequencing method Sanger
Isolation site Creosote-contaminated soil from the Champion International Superfund site in Libby Montana
Isolation country USA
Number of replicons 3
Gram staining properties Positive
Shape Bacilli
Mobility No
Flagellar presence No
Number of membranes 1
Oxygen requirements Aerobic
Optimal temperature NA
Temperature range Mesophilic
Habitat Multiple
Biotic relationship Free living
Host name NA
Cell arrangement Singles
Sporulation Nonsporulating
Metabolism PAH-degrading
Energy source Chemoorganotroph
Diseases None
Pathogenicity No