Bacillus thuringiensis str. Al Hakam

Names Bacillus thuringiensis str. Al Hakam
Accession numbers NC_008598, NC_008600
Background Bacillus thuringiensis is a Gram-positive, spore-forming bacterium that belongs to the B.cereus group along with Bacillus anthracis and Bacillus cereus. Bacillus thuringiensis is an insect pathogen that is widely used as a biopesticide in commercial agriculture due to its various endogenous crystal proteins and spores. When insects ingest toxin crystals (Cry), the alkaline pH of their digestive tract activates the toxin. Cry inserts into the insect gut cell membrane, forming a pore. The pore results cell lysis and eventual death of the insect.The parasporal crystals of B. thuringiensis are usually deposited against the forespore, develop outside the exosporium, and are separated from spores after sporulation. However, in a few cases, such as in B. thuringiensis serovar finitimus and serovar oyamesis strains the parasporal crystals are located between the exosporium and the spore coat and adhere to the spore after sporulation. This has been described as spore-crystal association (SCA); the crystal protein genes themselves (cry26Aa and cry28Aa) and their promoters cannot determine crystal formation inside the exosporium. This is the first genome sequence of B. thuringiensis harboring crystal protein genes (adapted from PMID 21398543). (EBI Integr8)
Strain Al Hakam
Complete Yes
Sequencing centre (14-NOV-2006) Joint Genome Institute, Department of Energy, 2800 Mitchell Drive, Walnut Creek, Ca 94598, USA
(28-NOV-2006) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA
Sequencing quality Level 6: Finished
Sequencing depth NA
Sequencing method NA
Isolation site Collected at a suspected bioweapons facility in Iraq
Isolation country NA
Number of replicons 2
Gram staining properties Positive
Shape Bacilli
Mobility Yes
Flagellar presence Yes
Number of membranes 1
Oxygen requirements Facultative
Optimal temperature NA
Temperature range Mesophilic
Habitat Multiple
Biotic relationship Free living
Host name Homo sapiens
Cell arrangement NA
Sporulation Sporulating
Metabolism NA
Energy source NA
Diseases Sotto disease
Pathogenicity No