Lactobacillus gasseri ATCC 33323
Names | Lactobacillus gasseri ATCC 33323 |
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Accession numbers | NC_008530 |
Background | Lactobacilli are normal inhabitants of the gastrointestinal tract of man and animals where they are widely considered to exert a number of beneficial roles including immunomodulation, interference with enteric pathogens, and maintenance of a healthy intestinal microflora. Historically, probiotic roles have been ascribed primarily to Lactobacillus acidophilus. The genus Lactobacillus presently comprises more than 50 recognized species of non pathogenic bacteria which in addition to their probiotic effects are useful to human as indispensable agents for the fermentation of foods and feed. Among these, Lactobacillus gasseri appears to represent the major homofermentative Lactobacillus species that occupies the human GI tract. This L. gasseri demonstrates good survival in the GI tract and has been associated with a variety of probiotic activities and roles including reduction of fecal mutagenic enzymes, adherence to intestinal tissues, stimulation of macrophages, and production of bacteriocins. Like other lactic acid bacteria, L.gasseri are acid tolerant, cannot synthesize porphyrins, and possess a strictly fermentative metabolism with lactic acid as the major metabolic end product (adapted from http://genome.jgi-psf.org/lacga/lacga.home.html). (EBI Integr8) |
Taxonomy | |
Kingdom: | Bacteria |
Phylum: | Firmicutes |
Class: | Bacilli |
Order: | Lactobacillales |
Family: | Lactobacillaceae |
Genus: | Lactobacillus |
Species: | gasseri |
Strain | ATCC 33323 |
Complete | Yes |
Sequencing centre | (22-MAY-2006) US DOE Joint Genome Institute, 2800 Mitchell Drive B100, Walnut Creek, CA 94598-1698, USA (24-OCT-2006) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA |
Sequencing quality | Level 6: Finished |
Sequencing depth | NA |
Sequencing method | NA |
Isolation site | "human mouth, gut and feces" |
Isolation country | NA |
Number of replicons | 1 |
Gram staining properties | Positive |
Shape | Bacilli |
Mobility | No |
Flagellar presence | No |
Number of membranes | 1 |
Oxygen requirements | Facultative |
Optimal temperature | 25.0 |
Temperature range | Mesophilic |
Habitat | HostAssociated |
Biotic relationship | Free living |
Host name | Homo sapiens |
Cell arrangement | Chains, Singles |
Sporulation | NA |
Metabolism | NA |
Energy source | NA |
Diseases | NA |
Pathogenicity | No |
Glycolysis / Gluconeogenesis
Pentose phosphate pathway
Galactose metabolism
Synthesis and degradation of ketone bodies
Purine metabolism
Pyrimidine metabolism
Alanine, aspartate and glutamate metabolism
D-Glutamine and D-glutamate metabolism
D-Alanine metabolism
Streptomycin biosynthesis
Peptidoglycan biosynthesis
One carbon pool by folate
Pantothenate and CoA biosynthesis
Terpenoid backbone biosynthesis
Aminoacyl-tRNA biosynthesis
Pentose phosphate pathway
Galactose metabolism
Synthesis and degradation of ketone bodies
Purine metabolism
Pyrimidine metabolism
Alanine, aspartate and glutamate metabolism
D-Glutamine and D-glutamate metabolism
D-Alanine metabolism
Streptomycin biosynthesis
Peptidoglycan biosynthesis
One carbon pool by folate
Pantothenate and CoA biosynthesis
Terpenoid backbone biosynthesis
Aminoacyl-tRNA biosynthesis