Streptococcus thermophilus LMD-9
Names | Streptococcus thermophilus LMD-9 |
---|---|
Accession numbers | NC_008500, NC_008501, NC_008532 |
Background | Lactobacilli are normal inhabitants of the gastrointestinal tract of man and animals where they are widely considered to exert a number of beneficial roles including immunomodulation, interference with enteric pathogens, and maintenance of a healthy intestinal microflora. Like other lacid acid bacteria they are acid tolerant, cannot synthesize prophyrins and are strictly fermentative with lactic acid as their major metabolic end product. Streptococcus thermophilus is used, along with Lactobacillus spp., as a starter culture for the manufacture of several important fermented dairy foods, including yogurt and mozzarella. Consequently, over 10(21) live cells are ingested annually by the human population. S. thermophilus has an important role as a probiotic, alleviating symptoms of lactose intolerance and other gastrointestinal disorders. Genes coding for metabolic pathways involved in sugar catabolism, protein and peptide utilization, polysaccharide production, the stress response system, and phage resistance mechanisms have been sequenced and characterized (adapted from http://genome.jgi-psf.org/strth/strth.home.html). (HAMAP: STRTD) |
Taxonomy | |
Kingdom: | Bacteria |
Phylum: | Firmicutes |
Class: | Bacilli |
Order: | Lactobacillales |
Family: | Streptococcaceae |
Genus: | Streptococcus |
Species: | thermophilus |
Strain | LMD-9 |
Complete | Yes |
Sequencing centre | (22-JUN-2006) US DOE Joint Genome Institute, 2800 Mitchell Drive B100, Walnut Creek, CA 94598-1698, USA (24-OCT-2006) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA |
Sequencing quality | Level 6: Finished |
Sequencing depth | NA |
Sequencing method | NA |
Isolation site | NA |
Isolation country | NA |
Number of replicons | 3 |
Gram staining properties | Positive |
Shape | Cocci |
Mobility | No |
Flagellar presence | No |
Number of membranes | 1 |
Oxygen requirements | Facultative |
Optimal temperature | 37.0 |
Temperature range | Mesophilic |
Habitat | Multiple |
Biotic relationship | Free living |
Host name | NA |
Cell arrangement | Chains, Pairs |
Sporulation | Nonsporulating |
Metabolism | Homofermentative |
Energy source | NA |
Diseases | None |
Pathogenicity | No |
Glycolysis / Gluconeogenesis
Citrate cycle (TCA cycle)
Purine metabolism
Pyrimidine metabolism
Alanine, aspartate and glutamate metabolism
Cysteine and methionine metabolism
Valine, leucine and isoleucine biosynthesis
Lysine biosynthesis
Histidine metabolism
Phenylalanine, tyrosine and tryptophan biosynthesis
Selenocompound metabolism
D-Glutamine and D-glutamate metabolism
D-Alanine metabolism
Streptomycin biosynthesis
Peptidoglycan biosynthesis
C5-Branched dibasic acid metabolism
One carbon pool by folate
Pantothenate and CoA biosynthesis
Folate biosynthesis
Terpenoid backbone biosynthesis
Aminoacyl-tRNA biosynthesis
Citrate cycle (TCA cycle)
Purine metabolism
Pyrimidine metabolism
Alanine, aspartate and glutamate metabolism
Cysteine and methionine metabolism
Valine, leucine and isoleucine biosynthesis
Lysine biosynthesis
Histidine metabolism
Phenylalanine, tyrosine and tryptophan biosynthesis
Selenocompound metabolism
D-Glutamine and D-glutamate metabolism
D-Alanine metabolism
Streptomycin biosynthesis
Peptidoglycan biosynthesis
C5-Branched dibasic acid metabolism
One carbon pool by folate
Pantothenate and CoA biosynthesis
Folate biosynthesis
Terpenoid backbone biosynthesis
Aminoacyl-tRNA biosynthesis