Helicobacter acinonychis str. Sheeba
Names | Helicobacter acinonychis str. Sheeba |
---|---|
Accession numbers | NC_008229, NC_008230 |
Background | Helicobacter acinonychis strain Sheeba is the causative agent of severe gastritis in large felines such as tigers, lions and cheetahs. H. acinonychis arose 200000 years ago via a host jump of H.pylori from early humans. Its genome is made up of one chromosome and one plasmid. It possesses a large number of highly fragmented genes, many encoding outer membrane proteins. These genes could have been destroyed in order to bypass deleterious responses from the feline host immune system. Five genes are present that are involved in sialylation of cell surface carbohydrates and that were probably acquired by horizontal gene transfer. (EBI Integr8) |
Taxonomy | |
Kingdom: | Bacteria |
Phylum: | Proteobacteria |
Class: | Epsilonproteobacteria |
Order: | Campylobacterales |
Family: | Helicobacteraceae |
Genus: | Helicobacter |
Species: | acinonychis |
Strain | Sheeba |
Complete | Yes |
Sequencing centre | (01-JUL-2006) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA (27-MAR-2006) Schuster S.C., Department of Biochemistry and Molecular Biology, Center for Comparative Genomics and |
Sequencing quality | Level 6: Finished |
Sequencing depth | NA |
Sequencing method | NA |
Isolation site | Biopsy of Russian circus lion with gastroenteritis |
Isolation country | NA |
Number of replicons | 2 |
Gram staining properties | Negative |
Shape | Spirilla |
Mobility | Yes |
Flagellar presence | Yes |
Number of membranes | 2 |
Oxygen requirements | Microaerophilic |
Optimal temperature | 37.0 |
Temperature range | Mesophilic |
Habitat | HostAssociated |
Biotic relationship | Free living |
Host name | Lion |
Cell arrangement | Singles |
Sporulation | Nonsporulating |
Metabolism | NA |
Energy source | NA |
Diseases | Gastric lesions |
Pathogenicity | NA |
Citrate cycle (TCA cycle)
Pentose phosphate pathway
Synthesis and degradation of ketone bodies
Purine metabolism
Pyrimidine metabolism
Alanine, aspartate and glutamate metabolism
Valine, leucine and isoleucine biosynthesis
Lysine biosynthesis
Phenylalanine, tyrosine and tryptophan biosynthesis
D-Glutamine and D-glutamate metabolism
D-Alanine metabolism
Lipopolysaccharide biosynthesis
Peptidoglycan biosynthesis
Riboflavin metabolism
Pantothenate and CoA biosynthesis
Biotin metabolism
Folate biosynthesis
Terpenoid backbone biosynthesis
Aminoacyl-tRNA biosynthesis
Biosynthesis of unsaturated fatty acids
Pentose phosphate pathway
Synthesis and degradation of ketone bodies
Purine metabolism
Pyrimidine metabolism
Alanine, aspartate and glutamate metabolism
Valine, leucine and isoleucine biosynthesis
Lysine biosynthesis
Phenylalanine, tyrosine and tryptophan biosynthesis
D-Glutamine and D-glutamate metabolism
D-Alanine metabolism
Lipopolysaccharide biosynthesis
Peptidoglycan biosynthesis
Riboflavin metabolism
Pantothenate and CoA biosynthesis
Biotin metabolism
Folate biosynthesis
Terpenoid backbone biosynthesis
Aminoacyl-tRNA biosynthesis
Biosynthesis of unsaturated fatty acids
NCBI Genomes
NC_008229NC_008230