Pseudomonas aeruginosa PAO1

Pseudomonas_aeruginosa
Names Pseudomonas aeruginosa PAO1
Accession numbers NC_002516
Background Pseudomonas aeruginosa are motile, mesophilic, Gram-negative rod bacterium that are noted for their environmental versatility. P. aeruginosa is increasingly recognised as a nosocomial pathogen, targetting immunocompromised individuals, cancer and burn victims, and individuals with in-dwelling catheters or using respirators. It is also the leading cause in mortality and morbidity for cystic fibrosis patients.Unlike many environmental bacteria, P. aeruginosa has the ability to adapt to and thrive in many ecological niches, from water and soil to plant and animal tissues. The bacterium is capable of utilising a wide range of organic compounds as food sources, thus giving it an exceptional ability to colonise where nutrients are limited.P. aeruginosa can produce a number of toxic proteins which not only cause extensive tissue damage, but also interfere with the human immune system's defense mechanisms. These proteins range from potent toxins that enter and kill host cells at or near the site of colonisation to degradative enzymes that permanently disrupt the cell membranes and connective tissues in various organs.(From http://www.ebi.ac.uk/2can/genomes/bacteria.html) (BacMap)
Taxonomy
Kingdom:Bacteria
Phylum:Proteobacteria
Class:Gammaproteobacteria
Order:Pseudomonadales
Family:Pseudomonadaceae
Genus:Pseudomonas
Species:aeruginosa
Strain PAO1
Complete Yes
Sequencing centre (02-OCT-2008) Department of Molecular Biology and Biochemisry, Simon Fraser University, 8888 University Dr., Burnaby,
(04-FEB-2003) Department of Molecular Biology and Biochemistry, Simon Fraser University, 8888 University Dr.,
(05-JUL-2006) Department of Molecular Biology and Biochemisry, Simon Fraser University, 8888 University Dr., Burnaby,
(06-OCT-2010) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA
(08-SEP-2010) Department of Molecular Biology and Biochemisry, Simon Fraser University, 8888 University Dr., Burnaby,
(16-MAY-2000) Department of Medicine and Genetics, University of Washington Genome Center, University Of Washington,
Sequencing quality Level 6: Finished
Sequencing depth NA
Sequencing method NA
Isolation site human infected wound
Isolation country NA
Number of replicons 1
Gram staining properties Negative
Shape Bacilli
Mobility Yes
Flagellar presence Yes
Number of membranes 2
Oxygen requirements Aerobic
Optimal temperature 25.0
Temperature range Mesophilic
Habitat Multiple
Biotic relationship Free living
Host name Homo sapiens
Cell arrangement Singles
Sporulation Nonsporulating
Metabolism NA
Energy source Heterotroph
Diseases Opportunistic infections
Pathogenicity NA