Burkholderia xenovorans LB400

Burkholderia_xenovorans
Names Burkholderia xenovorans LB400
Accession numbers NC_007951, NC_007952, NC_007953
Background Burkholderia xenovorans (strain LB400), has one of the largest known prokaryotic genomes (9.7 Mb) and is one of the best aerobic PCB degrading strains. It was isolated from a PCB-containing landfill near in upper New York State by a research team at General Electric Research. It oxidizes more than 20 PCB congeners including some with 4, 5 and 6 chlorine substitutions on the biphenyl rings. Three pathways for degradation of benzoate intermediates from biphenyl oxidation have been found in this organism. It also fixes nitrogen. This strain is known by many names. Originally it was described as Pseudomonas cepacia and later, in succession, Burkholderia cepacia, Burkholderia spp., Burkholderia fungorum. (EBI Integr8)
Taxonomy
Kingdom:Bacteria
Phylum:Proteobacteria
Class:Betaproteobacteria
Order:Burkholderiales
Family:Burkholderiaceae
Genus:Burkholderia
Species:xenovorans
Strain LB400
Complete Yes
Sequencing centre (11-APR-2006) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA
(13-MAR-2006) US DOE Joint Genome Institute, 2800 Mitchell Drive B100, Walnut Creek, CA 94598-1698, USA
Sequencing quality Level 6: Finished
Sequencing depth NA
Sequencing method NA
Isolation site soil; Moreau, New York, USA
Isolation country USA
Number of replicons 3
Gram staining properties Negative
Shape Bacilli
Mobility No
Flagellar presence Yes
Number of membranes 2
Oxygen requirements Aerobic
Optimal temperature 30.0
Temperature range Mesophilic
Habitat Multiple
Biotic relationship Free living
Host name Homo sapiens
Cell arrangement Singles
Sporulation Nonsporulating
Metabolism PCB degrading
Energy source NA
Diseases Opportunistic infections
Pathogenicity No
Glycolysis / Gluconeogenesis
Citrate cycle (TCA cycle)
Pentose phosphate pathway
Fructose and mannose metabolism
Ascorbate and aldarate metabolism
Fatty acid metabolism
Synthesis and degradation of ketone bodies
Ubiquinone and other terpenoid-quinone biosynthesis
Purine metabolism
Pyrimidine metabolism
Alanine, aspartate and glutamate metabolism
Glycine, serine and threonine metabolism
Cysteine and methionine metabolism
Valine, leucine and isoleucine degradation
Geraniol degradation
Valine, leucine and isoleucine biosynthesis
Lysine biosynthesis
Lysine degradation
Arginine and proline metabolism
Histidine metabolism
Tyrosine metabolism
Phenylalanine metabolism
Chlorocyclohexane and chlorobenzene degradation
Benzoate degradation
Bisphenol degradation
Fluorobenzoate degradation
Tryptophan metabolism
Phenylalanine, tyrosine and tryptophan biosynthesis
beta-Alanine metabolism
Taurine and hypotaurine metabolism
Selenocompound metabolism
Cyanoamino acid metabolism
D-Glutamine and D-glutamate metabolism
D-Arginine and D-ornithine metabolism
D-Alanine metabolism
Glutathione metabolism
Amino sugar and nucleotide sugar metabolism
Streptomycin biosynthesis
Lipopolysaccharide biosynthesis
Peptidoglycan biosynthesis
Pyruvate metabolism
Dioxin degradation
Xylene degradation
Toluene degradation
Polycyclic aromatic hydrocarbon degradation
Chloroalkane and chloroalkene degradation
Naphthalene degradation
Aminobenzoate degradation
Glyoxylate and dicarboxylate metabolism
Nitrotoluene degradation
Propanoate metabolism
Ethylbenzene degradation
Styrene degradation
Butanoate metabolism
C5-Branched dibasic acid metabolism
One carbon pool by folate
Methane metabolism
Thiamine metabolism
Riboflavin metabolism
Vitamin B6 metabolism
Nicotinate and nicotinamide metabolism
Pantothenate and CoA biosynthesis
Biotin metabolism
Lipoic acid metabolism
Folate biosynthesis
Atrazine degradation
Porphyrin and chlorophyll metabolism
Terpenoid backbone biosynthesis
Limonene and pinene degradation
Nitrogen metabolism
Sulfur metabolism
Caprolactam degradation
Aminoacyl-tRNA biosynthesis