Chlamydophila felis Fe/C-56

Names Chlamydophila felis Fe/C-56
Accession numbers NC_007899, NC_007900
Background Chlamydophila felis is the causative agent of conjunctivitis in cats. Although conjunctivitis is the major clinical sign, there may also be mild sneezing and nasal discharge in some affected cats. Occasionally there is a mild fever which can result in lethargy and inappetence but, generally, affected cats remain bright and eat well. If left untreated, the conjunctivitis often persists for six to eight weeks or longer and cats may continue to shed the organism for many months. Chlamydophila felis also causes pneumonitis and has been found in the gastrointestinal tract and reproductive tract of cats and there is some speculation that it may be a cause of infertility in breeding queens. Chlamydophila infection is relatively common in cats and up to 30% of cases of chronic conjunctivitis may be caused by this organism. The bacterium requires direct contact between cats to spread. Although cats of all ages can be infected, disease is seen most commonly in young kittens (5 - 12 weeks old) with persistent or recurrent infection. Seroepidemiologic studies have shown that the bacterium is present in 1.7% of the general human population and 8.8% of veterinarians in small animal clinics in Japan. The infection in human is most likely acquired from infected cats but rarely causes any serious illness in humans. The genome of C.felis is made up of one circular chromosome and one plasmid pCfe1. (EBI Integr8)
Strain Fe/C-56
Complete Yes
Sequencing centre (11-MAR-2006) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA
(19-MAY-2004) Kitasato Institute for Life Sciences, 1-15-1 Kitasato, Sagamihara, Kanagawa 228-8555, Japan
Sequencing quality Level 6: Finished
Sequencing depth NA
Sequencing method NA
Isolation site isolated from a cat with conjunctivitis.
Isolation country Japan
Number of replicons 2
Gram staining properties Negative
Shape Bacilli
Mobility No
Flagellar presence No
Number of membranes 2
Oxygen requirements NA
Optimal temperature 37.0
Temperature range Mesophilic
Habitat HostAssociated
Biotic relationship Symbiotic
Host name Cat
Cell arrangement NA
Sporulation NA
Metabolism NA
Energy source NA
Diseases Pharyngitis, bronchitis and pneumonitis
Pathogenicity No