Campylobacter jejuni subsp. jejuni NCTC 11168
Names | Campylobacter jejuni subsp. jejuni NCTC 11168 |
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Accession numbers | NC_002163 |
Background | Campylobacter jejuni strain NCTC11168. This strain (originally 5636/77) was isolated from a diarrheic patient in 1977 and minimally passaged. This strain displays aberrant virulence phenotypes in animal models and tissue culture. Contains many homopolymeric tracts in the genome which result in hypervariable sequences in many genes having to do with cell surface structures. These sequences result in hypervarible antigenic diversity and immune evasion. Overall, the genome contains very few repetitive DNA sequences and very few coding regions arranged in operons. Pathogenicity factors include cytolethal-distending toxin, hemolysin-like toxins, and a type II secretion system. (NCBI BioProject: bp_list[1]) |
Taxonomy | |
Kingdom: | Bacteria |
Phylum: | Proteobacteria |
Class: | Epsilonproteobacteria |
Order: | Campylobacterales |
Family: | Campylobacteraceae |
Genus: | Campylobacter |
Species: | jejuni |
Strain | NCTC 11168 |
Complete | Yes |
Sequencing centre | (07-AUG-2006) sequencing team, Sanger Centre, Wellcome Trust Genome Campus, (09-FEB-2000) sequencing team, Sanger Centre, Wellcome Trust Genome Campus, (12-DEC-2008) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA |
Sequencing quality | Level 6: Finished |
Sequencing depth | NA |
Sequencing method | Sanger |
Isolation site | Diarrheic patient in 1977 |
Isolation country | NA |
Number of replicons | 1 |
Gram staining properties | Negative |
Shape | Spirilla |
Mobility | No |
Flagellar presence | Yes |
Number of membranes | 2 |
Oxygen requirements | Microaerophilic |
Optimal temperature | NA |
Temperature range | Mesophilic |
Habitat | Multiple |
Biotic relationship | Free living |
Host name | Homo sapiens |
Cell arrangement | Chains, Singles |
Sporulation | Nonsporulating |
Metabolism | NA |
Energy source | Heterotroph |
Diseases | Food poisoning |
Pathogenicity | Yes |
Citrate cycle (TCA cycle)
Pentose phosphate pathway
Purine metabolism
Pyrimidine metabolism
Alanine, aspartate and glutamate metabolism
Valine, leucine and isoleucine biosynthesis
Lysine biosynthesis
Histidine metabolism
Phenylalanine, tyrosine and tryptophan biosynthesis
Selenocompound metabolism
D-Glutamine and D-glutamate metabolism
D-Alanine metabolism
Lipopolysaccharide biosynthesis
Peptidoglycan biosynthesis
C5-Branched dibasic acid metabolism
One carbon pool by folate
Thiamine metabolism
Pantothenate and CoA biosynthesis
Biotin metabolism
Folate biosynthesis
Terpenoid backbone biosynthesis
Aminoacyl-tRNA biosynthesis
Pentose phosphate pathway
Purine metabolism
Pyrimidine metabolism
Alanine, aspartate and glutamate metabolism
Valine, leucine and isoleucine biosynthesis
Lysine biosynthesis
Histidine metabolism
Phenylalanine, tyrosine and tryptophan biosynthesis
Selenocompound metabolism
D-Glutamine and D-glutamate metabolism
D-Alanine metabolism
Lipopolysaccharide biosynthesis
Peptidoglycan biosynthesis
C5-Branched dibasic acid metabolism
One carbon pool by folate
Thiamine metabolism
Pantothenate and CoA biosynthesis
Biotin metabolism
Folate biosynthesis
Terpenoid backbone biosynthesis
Aminoacyl-tRNA biosynthesis