Campylobacter jejuni subsp. jejuni NCTC 11168

Names Campylobacter jejuni subsp. jejuni NCTC 11168
Accession numbers NC_002163
Background Campylobacter jejuni strain NCTC11168. This strain (originally 5636/77) was isolated from a diarrheic patient in 1977 and minimally passaged. This strain displays aberrant virulence phenotypes in animal models and tissue culture. Contains many homopolymeric tracts in the genome which result in hypervariable sequences in many genes having to do with cell surface structures. These sequences result in hypervarible antigenic diversity and immune evasion. Overall, the genome contains very few repetitive DNA sequences and very few coding regions arranged in operons. Pathogenicity factors include cytolethal-distending toxin, hemolysin-like toxins, and a type II secretion system. (NCBI BioProject: bp_list[1])
Strain NCTC 11168
Complete Yes
Sequencing centre (07-AUG-2006) sequencing team, Sanger Centre, Wellcome Trust Genome Campus,
(09-FEB-2000) sequencing team, Sanger Centre, Wellcome Trust Genome Campus,
(12-DEC-2008) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA
Sequencing quality Level 6: Finished
Sequencing depth NA
Sequencing method Sanger
Isolation site Diarrheic patient in 1977
Isolation country NA
Number of replicons 1
Gram staining properties Negative
Shape Spirilla
Mobility No
Flagellar presence Yes
Number of membranes 2
Oxygen requirements Microaerophilic
Optimal temperature NA
Temperature range Mesophilic
Habitat Multiple
Biotic relationship Free living
Host name Homo sapiens
Cell arrangement Chains, Singles
Sporulation Nonsporulating
Metabolism NA
Energy source Heterotroph
Diseases Food poisoning
Pathogenicity Yes