Haemophilus influenzae 86-028NP

Haemophilus_influenzae
Names Haemophilus influenzae 86-028NP
Accession numbers NC_007146
Background Haemophilus influenzae is a small, non-motile Gram-negative bacterium in the family Pasteurellaceae. Naturally-acquired disease caused by Haemophilus influenzae seems to occur in humans only. It was first isolated by Pfeiffer during the influenza pandemic of 1890. It was mistakenly thought to be the cause of the disease influenza, and it was named accordingly.Haemophilus influenzae is highly adapted to its human host. It is present in the nasopharynx of approximately 75 percent of healthy children and adults. It is rarely encountered in the oral cavity and it has not been detected in any other animal species.In infants and young children (under 5 years of age), Haemophilus influenzae type b causes bacteremia and acute bacterial meningitis Occasionally, it causes epiglottitis (obstructive laryngitis), cellulitis, osteomyelitis, and joint infections. Nontypable H. influenzae causes ear infections (otitis media) and sinusitis in children. Initially H. influenzae invades the nasopharyngeal mucosa before spreading to the lower respiratory tract where the organism invades and destroys the mucous membranes producing bronchiolitis, peribronchiolitis, and/or interstitial lesions and is associated with respiratory tract infections (pneumonia).In 1995, Haemophilus influenzae was the first free-living organism to have its entire chromosome sequenced. (From http://www.ebi.ac.uk/2can/genomes/bacteria.html) (BacMap)
Taxonomy
Kingdom:Bacteria
Phylum:Proteobacteria
Class:Gammaproteobacteria
Order:Pasteurellales
Family:Pasteurellaceae
Genus:Haemophilus
Species:influenzae
Strain 86-028NP
Complete Yes
Sequencing centre (22-MAR-2005) Pediatrics, Columbus Children's Research Institute, and The Ohio State University, 700 Children's Drive,
(27-JUN-2005) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA
Sequencing quality Level 6: Finished
Sequencing depth NA
Sequencing method NA
Isolation site 1890s during an influenza pandemic by Pfeiffer
Isolation country NA
Number of replicons 1
Gram staining properties Negative
Shape Bacilli
Mobility No
Flagellar presence No
Number of membranes 2
Oxygen requirements Facultative
Optimal temperature 35.0
Temperature range Mesophilic
Habitat HostAssociated
Biotic relationship Free living
Host name Homo sapiens
Cell arrangement NA
Sporulation NA
Metabolism NA
Energy source NA
Diseases Meningitis, speticemia, otitis media, sinusitis, chronic bronchitis
Pathogenicity Yes