Bacteroides fragilis YCH46

Names Bacteroides fragilis YCH46
Accession numbers NC_006297, NC_006347
Background Bacteroides fragilis strain YCH46. This organism can become an opportunistic pathogen, infecting anywhere in the body and causing abcess formation. Enterotoxigenic Bacterioides fragilis (ETBF) is associated with diarrheal diseases. This strain was isolated from a patient with septicemia in Japan. Virulence functions include numerous capsular polysaccharide biosynthesis systems that are controlled by invertible promoters that are recombined by a site-specific recombinase, Mpi, that works at a set of inverted repeats found within the chromosome. This system allows a vast repertoire of variable antigens to be expressed, thereby aiding evasion of the immune system. This organism also carries a potentially conjugative plasmid, as well as a number of conjugative and mobilizable transposons. (NCBI BioProject: bp_list[1])
Strain YCH46
Complete Yes
Sequencing centre (01-OCT-2004) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA
(20-APR-2004) Kitasato Institute for Life Sciences, 1-15-1, Kitasato, Sagamihara, Kanagawa 228-8555, Japan
Sequencing quality Level 6: Finished
Sequencing depth NA
Sequencing method NA
Isolation site Isolated from a patient with septicemia in Japan
Isolation country Japan
Number of replicons 2
Gram staining properties Negative
Shape Bacilli
Mobility No
Flagellar presence No
Number of membranes 2
Oxygen requirements Anaerobic
Optimal temperature 37.0
Temperature range Mesophilic
Habitat HostAssociated
Biotic relationship Free living
Host name Homo sapiens
Cell arrangement Singles
Sporulation NA
Metabolism NA
Energy source Chemoorganotroph
Diseases Severe infection, diarrhea, and abcesses
Pathogenicity Yes