Chlamydia trachomatis L2c
| Names | Chlamydia trachomatis L2c |
|---|---|
| Accession numbers | NC_015744 |
| Background | Chlamydia trachomatis infection is an important cause of preventable blindness and sexually transmitted disease (STD) in humans. There are 15 serovariants that exhibit distinct organotropism for the eye or the urogenital tract and are separated according to the pathobiotypes. Trachoma biovariants consist of serovars A, B, Ba, C, D, E, F, G, H, I, J and K. LGV (Lymphogranuloma venereum) biovariants consist of serovars L1, L2 and L3. Trachoma biovariants are noninvasive and epitheliotropic strains that cause blinding trachoma (A to C) or sexually transmitted diseases. LGV biovariants cause sexually transmitted diseases with disseminating infection of draining regional lymph nodes. The trpBA operon encoding tryptophan synthase is functional in STD serovars, whereas trpBA harbors mutations that inactivate the enzyme in ocular serovars. Chlamydia trachomatis is an obligate intracellular parasite depending on the host machinery for ATP synthesis. Chlamydial life cycle comprehends an intracellular metabolically- active "reticular body" and an inert extracellular spore-like "elementary body" equipped with a unique disulfide-cross-linked protein envelope. Chlamydia trachomatis (strain D/UW-3) is a genitotropic isolate. (EBI Integr8) |
| Taxonomy | |
| Kingdom: | Bacteria |
| Phylum: | Chlamydiae |
| Class: | Chlamydiae |
| Order: | Chlamydiales |
| Family: | Chlamydiaceae |
| Genus: | Chlamydia |
| Species: | trachomatis |
| Strain | L2c |
| Complete | Yes |
| Sequencing centre | (06-JUL-2011) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA (30-APR-2010) Department of Medicine, Division of Infectious Diseases, Emory University School of Medicine, 615 |
| Sequencing quality | Level 6: Finished |
| Sequencing depth | NA |
| Sequencing method | NA |
| Isolation site | man with severe proctitis. |
| Isolation country | NA |
| Number of replicons | 1 |
| Gram staining properties | Negative |
| Shape | Bacilli |
| Mobility | No |
| Flagellar presence | No |
| Number of membranes | 2 |
| Oxygen requirements | NA |
| Optimal temperature | NA |
| Temperature range | Mesophilic |
| Habitat | HostAssociated |
| Biotic relationship | Symbiotic |
| Host name | Homo sapiens |
| Cell arrangement | NA |
| Sporulation | NA |
| Metabolism | NA |
| Energy source | NA |
| Diseases | NA |
| Pathogenicity | Yes |
Citrate cycle (TCA cycle)
Pyrimidine metabolism
Lipopolysaccharide biosynthesis
Peptidoglycan biosynthesis
One carbon pool by folate
Riboflavin metabolism
Lipoic acid metabolism
Terpenoid backbone biosynthesis
Aminoacyl-tRNA biosynthesis
Pyrimidine metabolism
Lipopolysaccharide biosynthesis
Peptidoglycan biosynthesis
One carbon pool by folate
Riboflavin metabolism
Lipoic acid metabolism
Terpenoid backbone biosynthesis
Aminoacyl-tRNA biosynthesis