Mycobacterium sp. JDM601

Mycobacterium_sp.
Names Mycobacterium sp. JDM601
Accession numbers NC_015576
Background Mycobacteria belong to the order Actinomycetales that are Gram-positive, acid-fast, pleomorphic, non-motile rods characterized by distinctive cell surface mycolic acid derivatives. This isolate belongs to a fast-growing group and actually has a coccus morphology, whereas members of the slow-growing group of Mycobacteria are notorious for causing human and animal diseases. Mycobacterium JLS was isolated from soil in Libby, Montana, USA, the site of a former lumber and plywood mill. The soil is contaminated by polycyclic aromatic hydrocarbons (PAH), and JLS is one of several indigenous mycobacteria isolated from this site that are able to degrade high molecular weight PAH including pyrene, however this isolate cannot degrade benzo(a)pyrene. Other Mycobacteria from this site include strain MCS (MYCSS) and strain KMS (MYCSK). Strain JLS mineralizes small- and large-ring PAHs, in contrast to other PAH-degrading microbes and thus offers possibilities for bioremediation of PAHs. The genome sequence of the Mycobacterium isolate JLS will permit comparisons with the genomes of pathogenic isolates, as well as an understanding of the pathway for PAH degradation and survival mechanisms in polluted conditions (modified from http://genome.jgi-psf.org/finished_microbes/myc_j/myc_j.home.html). (HAMAP: MYCSJ)
Taxonomy
Kingdom:Bacteria
Phylum:Actinobacteria
Class:Actinobacteria
Order:Actinomycetales
Family:Mycobacteriaceae
Genus:Mycobacterium
Species:JDM601
Strain 506
Complete Yes
Sequencing centre (12-NOV-2010) Department of Medical Microbiology and Parasitology, Institutes of Medical Sciences, Shanghai Jiao Tong
(24-MAY-2011) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA
Sequencing quality Level 6: Finished
Sequencing depth NA
Sequencing method 454-GS-FLX
Isolation site patient with tubersulosis-like disease and with high resistance to various antibiotics
Isolation country NA
Number of replicons 1
Gram staining properties Positive
Shape Bacilli
Mobility No
Flagellar presence No
Number of membranes 1
Oxygen requirements Aerobic
Optimal temperature NA
Temperature range Mesophilic
Habitat HostAssociated
Biotic relationship Free living
Host name Homo sapiens
Cell arrangement Singles
Sporulation Nonsporulating
Metabolism NA
Energy source NA
Diseases NA
Pathogenicity No