Mycoplasma penetrans HF-2
| Names | Mycoplasma penetrans HF-2 |
|---|---|
| Accession numbers | NC_004432 |
| Background | This human pathogen infects the urogenital and respiratory tracts. As the name indicates, Mycoplasma penetrans typically penetrates human cells.First reported in 1993 as an emerging infectious agent, this gram positive bacterium is mainly associated with HIV infections but has been implicated in non-HIV related diseases. 20-40% of the HIV-positive homosexual population in Europe and the U. S. A. are infected with Mycoplasma penetrans. Anti-Mycoplasma penetrans antibodies are developed even in asymptomatic HIV carriers and in patients in the process of developing AIDS.Since Mycoplasma penetrans has mitogenic activity to lymphocytes from HIV-infected individuals, it may be suggested that persistent M. penetrans infection may contribute to the deterioration of the immune system in HIV-infection. Mycoplasma penetrans infection has also been suggested to be a primary cause of human disease in non-HIV-related urethritis and respiratory disease.(From http://www.ebi.ac.uk/2can/genomes/bacteria.html) (BacMap) |
| Taxonomy | |
| Kingdom: | Bacteria |
| Phylum: | Tenericutes |
| Class: | Mollicutes |
| Order: | Mycoplasmatales |
| Family: | Mycoplasmataceae |
| Genus: | Mycoplasma |
| Species: | penetrans |
| Strain | HF-2 |
| Complete | Yes |
| Sequencing centre | (11-SEP-2004) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA (25-JUN-2001) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA |
| Sequencing quality | Level 6: Finished |
| Sequencing depth | NA |
| Sequencing method | NA |
| Isolation site | NA |
| Isolation country | NA |
| Number of replicons | 1 |
| Gram staining properties | Negative |
| Shape | Cocci |
| Mobility | No |
| Flagellar presence | No |
| Number of membranes | 1 |
| Oxygen requirements | Facultative |
| Optimal temperature | 37.0 |
| Temperature range | Mesophilic |
| Habitat | HostAssociated |
| Biotic relationship | Free living |
| Host name | Homo sapiens |
| Cell arrangement | Singles |
| Sporulation | Nonsporulating |
| Metabolism | NA |
| Energy source | NA |
| Diseases | Urogenital or respiratory tract infections |
| Pathogenicity | Yes |
Glycolysis / Gluconeogenesis
Pyrimidine metabolism
One carbon pool by folate
Aminoacyl-tRNA biosynthesis
Pyrimidine metabolism
One carbon pool by folate
Aminoacyl-tRNA biosynthesis