Lactobacillus acidophilus 30SC
Names | Lactobacillus acidophilus 30SC |
---|---|
Accession numbers | NC_015213, NC_015214, NC_015218 |
Background | Lactobacilli are normal inhabitants of the gastrointestinal tract of man and animals where they are widely considered to exert a number of beneficial roles including immunomodulation, interference with enteric pathogens, and maintenance of a healthy intestinal microflora. Historically, probiotic roles have been ascribed primarily to Lactobacillus acidophilus. The genus Lactobacillus presently comprises more than 50 recognized species of non pathogenic bacteria which in addition to their probiotic effects are useful to human as indispensable agents for the fermentation of foods and feed. Lactobacillus acidophilus is part of the human oral, gastrointestinal, and vaginal microbial flora. This organism has been studied for its ability to help the human gut maintain its natural microbial community. Strains of this organism are also used in the production of yogurt, cheese and other fermented foods. Lactobacillus acidophilus (strain 30SC) is a probiotic Gram-positive bacterium isolated from swine intestine showing strong acid tolerance and bile resistance. L. acidophilus 30SC produces a bacteriocin that is active over a wide range of pH range and inhibits many gram-positive pathogenic strains. It can be utilized as a potential probiotic culture incorporated in dairy foods and dietary supplements. (Adapted from PMID: 21478365 and http://www.ncbi.nlm.nih.gov/genomeprj?Db=genomeprj&cmd=ShowDetailView&TermToSearch=53145). (EBI Integr8) |
Taxonomy | |
Kingdom: | Bacteria |
Phylum: | Firmicutes |
Class: | Bacilli |
Order: | Lactobacillales |
Family: | Lactobacillaceae |
Genus: | Lactobacillus |
Species: | acidophilus |
Strain | 30SC |
Complete | Yes |
Sequencing centre | (10-MAR-2011) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA (28-FEB-2011) Computational and Synthetic Biology Laboratory, Korea University, Anam Campus, Anam-dong 5-ga, |
Sequencing quality | Level 6: Finished |
Sequencing depth | NA |
Sequencing method | NA |
Isolation site | swine instestine |
Isolation country | Korea |
Number of replicons | 3 |
Gram staining properties | Positive |
Shape | Bacilli |
Mobility | No |
Flagellar presence | No |
Number of membranes | 1 |
Oxygen requirements | Facultative |
Optimal temperature | NA |
Temperature range | Mesophilic |
Habitat | HostAssociated |
Biotic relationship | Free living |
Host name | Sus Scrofa |
Cell arrangement | NA |
Sporulation | NA |
Metabolism | NA |
Energy source | NA |
Diseases | NA |
Pathogenicity | No |
Glycolysis / Gluconeogenesis
Pentose phosphate pathway
Galactose metabolism
Synthesis and degradation of ketone bodies
Purine metabolism
Pyrimidine metabolism
Alanine, aspartate and glutamate metabolism
Lysine biosynthesis
Selenocompound metabolism
D-Glutamine and D-glutamate metabolism
D-Alanine metabolism
Peptidoglycan biosynthesis
One carbon pool by folate
Thiamine metabolism
Pantothenate and CoA biosynthesis
Terpenoid backbone biosynthesis
Aminoacyl-tRNA biosynthesis
Pentose phosphate pathway
Galactose metabolism
Synthesis and degradation of ketone bodies
Purine metabolism
Pyrimidine metabolism
Alanine, aspartate and glutamate metabolism
Lysine biosynthesis
Selenocompound metabolism
D-Glutamine and D-glutamate metabolism
D-Alanine metabolism
Peptidoglycan biosynthesis
One carbon pool by folate
Thiamine metabolism
Pantothenate and CoA biosynthesis
Terpenoid backbone biosynthesis
Aminoacyl-tRNA biosynthesis