Mycoplasma haemofelis str. Langford 1
| Names | Mycoplasma haemofelis str. Langford 1 |
|---|---|
| Accession numbers | NC_014970 |
| Background | This genus currently comprizes more than 120 obligate parasitic species found in the wide spectrum of hosts, including humans, animals, insects and plants. Infection proceeds through attachment of the bacteria to the host cell via specialized surface proteins, adhesins, and subsequent invation, results in prolonged intracellular persistence that may cause lethality. All mycoplasmas are phenotypically distinguished from other bacteria by their small size (0.3-0.8 micron in diameter) and lack of a cell wall. The latter is one of the major traits that puts them in the separate taxonomic group of microorganisms, class Mollicutes. The cell membrane is rich in protein component (up to two thirds of the membrane mass) that to a great extent consists of highly structurally adaptive lipoproteins employed in invading the host immune system, attachment to the host cells and pathogenic invasion. Most mycoplasmas are non-motile. Mycoplasma haemofelis is a pathogenic hemotropicmycoplasma (trivial name, hemoplasma) that can induce hemolyticanemia, also known as hemobartonellosis, in cats. The extracellular pleomorphic bacterium attaches to the surface of feline erythrocytes causing hemolytic anemia through extravascular destruction of erythrocytes by the mononuclear phagocyte system and intravascular lysis by direct damage to the cell membrane, increased osmotic fragility, or both. Following recovery from infection, many cats appear to harbor the organism in a latent carrier state (adapted from PMID 21317334 and 15510683). (EBI Integr8) |
| Taxonomy | |
| Kingdom: | Bacteria |
| Phylum: | Tenericutes |
| Class: | NA |
| Order: | NA |
| Family: | NA |
| Genus: | NA |
| Species: | NA |
| Strain | Langford 1 |
| Complete | Yes |
| Sequencing centre | (10-JAN-2011) Barker E., School of Clinical Veterinary Sciences, VPII, University of Bristol, Churchill Building, Langford (27-JAN-2011) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA |
| Sequencing quality | Level 6: Finished |
| Sequencing depth | NA |
| Sequencing method | 454-GS-FLX, 454-GS-FLX-Titanium |
| Isolation site | blood taken from an experimentally infected specific pathogen free (SPF)-derived cat at a time of high parasitemia |
| Isolation country | NA |
| Number of replicons | 1 |
| Gram staining properties | Positive |
| Shape | NA |
| Mobility | No |
| Flagellar presence | No |
| Number of membranes | 1 |
| Oxygen requirements | Facultative |
| Optimal temperature | NA |
| Temperature range | Mesophilic |
| Habitat | HostAssociated |
| Biotic relationship | Free living |
| Host name | Felis catus (Cat) |
| Cell arrangement | Singles |
| Sporulation | Nonsporulating |
| Metabolism | NA |
| Energy source | NA |
| Diseases | NA |
| Pathogenicity | No |