Mycoplasma haemofelis str. Langford 1

Mycoplasma_haemofelis
Names Mycoplasma haemofelis str. Langford 1
Accession numbers NC_014970
Background This genus currently comprizes more than 120 obligate parasitic species found in the wide spectrum of hosts, including humans, animals, insects and plants. Infection proceeds through attachment of the bacteria to the host cell via specialized surface proteins, adhesins, and subsequent invation, results in prolonged intracellular persistence that may cause lethality. All mycoplasmas are phenotypically distinguished from other bacteria by their small size (0.3-0.8 micron in diameter) and lack of a cell wall. The latter is one of the major traits that puts them in the separate taxonomic group of microorganisms, class Mollicutes. The cell membrane is rich in protein component (up to two thirds of the membrane mass) that to a great extent consists of highly structurally adaptive lipoproteins employed in invading the host immune system, attachment to the host cells and pathogenic invasion. Most mycoplasmas are non-motile. Mycoplasma haemofelis is a pathogenic hemotropicmycoplasma (trivial name, hemoplasma) that can induce hemolyticanemia, also known as hemobartonellosis, in cats. The extracellular pleomorphic bacterium attaches to the surface of feline erythrocytes causing hemolytic anemia through extravascular destruction of erythrocytes by the mononuclear phagocyte system and intravascular lysis by direct damage to the cell membrane, increased osmotic fragility, or both. Following recovery from infection, many cats appear to harbor the organism in a latent carrier state (adapted from PMID 21317334 and 15510683). (EBI Integr8)
Taxonomy
Kingdom:Bacteria
Phylum:Tenericutes
Class:NA
Order:NA
Family:NA
Genus:NA
Species:NA
Strain Langford 1
Complete Yes
Sequencing centre (10-JAN-2011) Barker E., School of Clinical Veterinary Sciences, VPII, University of Bristol, Churchill Building, Langford
(27-JAN-2011) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA
Sequencing quality Level 6: Finished
Sequencing depth NA
Sequencing method 454-GS-FLX, 454-GS-FLX-Titanium
Isolation site blood taken from an experimentally infected specific pathogen free (SPF)-derived cat at a time of high parasitemia
Isolation country NA
Number of replicons 1
Gram staining properties Positive
Shape NA
Mobility No
Flagellar presence No
Number of membranes 1
Oxygen requirements Facultative
Optimal temperature NA
Temperature range Mesophilic
Habitat HostAssociated
Biotic relationship Free living
Host name Felis catus (Cat)
Cell arrangement Singles
Sporulation Nonsporulating
Metabolism NA
Energy source NA
Diseases NA
Pathogenicity No