Neisseria lactamica 020-06
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Names | Neisseria lactamica 020-06 |
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Accession numbers | NC_014752 |
Background | The genus Neisseria, which comprises oxidase positive diplococci that colonise the mucosa of humans and animals, includes species that are never or rarely pathogenic and two human pathogens of global significance, Neisseria meningitidis and Neisseria gonorrhoeae. Neisseria lactamica is closely related to the pathogenic Neisseria and, like them, is only ever isolated from humans. N. lactamica is an obligate commensal inhabitant of the human nasopharynx that establishes long-term normally asymptomatic colonisation. Occurrence of N. lactamica is high in infants and young children and declines as the age of the human host population rises. It has been suggested that colonisation of children with N. lactamica plays a role in the development of immunity to the meningococcus, and anti-meningococcal vaccines based N. lactamica have been proposed at various times. Strain 020-06 belongs to sequence type ST-640 and was isolated from a six-week-old child from the UK in 1997. A plasmid of 3,151 bp was present in the organism but does not seem to have been submitted to the INSDC database (adapted from PMID 21092259). (EBI Integr8) |
Taxonomy | |
Kingdom: | Bacteria |
Phylum: | Proteobacteria |
Class: | Betaproteobacteria |
Order: | Neisseriales |
Family: | Neisseriaceae |
Genus: | Neisseria |
Species: | lactamica |
Strain | ST-640 |
Complete | Yes |
Sequencing centre | (03-DEC-2010) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA (18-JUN-2010) Bentley S.D., Pathogen Genomics, Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, |
Sequencing quality | Level 6: Finished |
Sequencing depth | NA |
Sequencing method | NA |
Isolation site | nasopharyngeal culture |
Isolation country | NA |
Number of replicons | 1 |
Gram staining properties | Negative |
Shape | Cocci |
Mobility | No |
Flagellar presence | No |
Number of membranes | 2 |
Oxygen requirements | Aerobic |
Optimal temperature | NA |
Temperature range | Mesophilic |
Habitat | HostAssociated |
Biotic relationship | Free living |
Host name | Homo sapiens |
Cell arrangement | Pairs |
Sporulation | Nonsporulating |
Metabolism | NA |
Energy source | NA |
Diseases | NA |
Pathogenicity | No |
Glycolysis / Gluconeogenesis
Citrate cycle (TCA cycle)
Pentose phosphate pathway
Purine metabolism
Pyrimidine metabolism
Alanine, aspartate and glutamate metabolism
Glycine, serine and threonine metabolism
Cysteine and methionine metabolism
Valine, leucine and isoleucine biosynthesis
Lysine biosynthesis
Histidine metabolism
Phenylalanine, tyrosine and tryptophan biosynthesis
Selenocompound metabolism
D-Glutamine and D-glutamate metabolism
D-Alanine metabolism
Streptomycin biosynthesis
Lipopolysaccharide biosynthesis
Peptidoglycan biosynthesis
Pyruvate metabolism
C5-Branched dibasic acid metabolism
One carbon pool by folate
Thiamine metabolism
Riboflavin metabolism
Vitamin B6 metabolism
Nicotinate and nicotinamide metabolism
Pantothenate and CoA biosynthesis
Lipoic acid metabolism
Folate biosynthesis
Terpenoid backbone biosynthesis
Sulfur metabolism
Aminoacyl-tRNA biosynthesis
Citrate cycle (TCA cycle)
Pentose phosphate pathway
Purine metabolism
Pyrimidine metabolism
Alanine, aspartate and glutamate metabolism
Glycine, serine and threonine metabolism
Cysteine and methionine metabolism
Valine, leucine and isoleucine biosynthesis
Lysine biosynthesis
Histidine metabolism
Phenylalanine, tyrosine and tryptophan biosynthesis
Selenocompound metabolism
D-Glutamine and D-glutamate metabolism
D-Alanine metabolism
Streptomycin biosynthesis
Lipopolysaccharide biosynthesis
Peptidoglycan biosynthesis
Pyruvate metabolism
C5-Branched dibasic acid metabolism
One carbon pool by folate
Thiamine metabolism
Riboflavin metabolism
Vitamin B6 metabolism
Nicotinate and nicotinamide metabolism
Pantothenate and CoA biosynthesis
Lipoic acid metabolism
Folate biosynthesis
Terpenoid backbone biosynthesis
Sulfur metabolism
Aminoacyl-tRNA biosynthesis