Rhodococcus equi 103S

Rhodococcus_equi
Names Rhodococcus equi 103S
Accession numbers NC_014659
Background Rhodococci are aerobic, Gram positive actinomycetes of high G+C content, capable of morphological differentiation in response to their environment (e.g., cocci or filaments). These widely occurring organisms are of considerable environmental and biotechnological importance due to their broad metabolic diversity and array of unique enzymatic capabilities. These are of interest to the pharmaceutical, environmental, chemical and energy sectors. Rhodococci are well suited for bioremediation due to their capacity for long term survival in soil, their exceptional ability to degrade hydrophobic pollutants even in the presence of more readily assimilable carbon sources, and their ability to accumulate high levels of heavy metals. The Rhodococci also include an animal pathogen, Rhodococcus equi.R.equi is a strictly aerobic, soil-dwelling, multihost pathogen that causes purulent infections in various animals. In horses, it causes rattles, a lung disease with a high mortality in foals. It is transmitted by the inhalation of contaminated soil dust or the breath of infected animals. It causes chronic pyogranulomatous adenitis in pigs and cattle and severe opportunistic infections in humans, often in HIV-infected and immunosuppressed patients. It is a facultative intracellular pathogen, parasitizing macrophages rather like Mycobacterium tuberculosis. This strain is the original stock of the foal clinical isolate 103, named 103S. Comparison with non-pathogenic Rhodococcus shows that strain 103S has many fewer catabolic and secondary metabolic capabilities and has adapted to live in the mammalian intestine and manure, its main reservoirs (adapted from PMID 20941392). (EBI Integr8)
Taxonomy
Kingdom:Bacteria
Phylum:Actinobacteria
Class:Actinobacteria
Order:Actinomycetales
Family:Nocardiaceae
Genus:Rhodococcus
Species:equi
Strain 103S
Complete Yes
Sequencing centre (12-NOV-2010) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA
(21-OCT-2009) Vazquez-Boland J.A., University of Edinburgh, Centre for Infectious Diseases, Edinburgh, EH9 3JT,
Sequencing quality Level 6: Finished
Sequencing depth NA
Sequencing method NA
Isolation site NA
Isolation country NA
Number of replicons 1
Gram staining properties Positive
Shape Bacilli
Mobility No
Flagellar presence NA
Number of membranes 1
Oxygen requirements Aerobic
Optimal temperature NA
Temperature range Mesophilic
Habitat Multiple
Biotic relationship Free living
Host name NA
Cell arrangement Filaments
Sporulation Nonsporulating
Metabolism NA
Energy source NA
Diseases Pneumonia
Pathogenicity Yes