Streptococcus pneumoniae AP200
Names | Streptococcus pneumoniae AP200 |
---|---|
Accession numbers | NC_014494 |
Background | A Gram-positive nonmotile bacterium, Streptococcus pneumoniae is the most common bacterial cause of acute respiratory infection and otitis media, and is estimated to result in over 1 millions deaths in children, the elderly, debilitated and immunosuppressed people every year. Since 1990 the number of penicillin-resistant strains has increased and many strains are now resistant to commonly prescribed antibiotics such as penicillin, macrolides and fluoroquinones. Strain AP200 is a clinical strain isolated in Italy in 2003 from the cerebrospinal fluid of a patient with meningitis. It is serotype 11A and sequence type (ST) 2003, which is a single-locus variant of ST62. It is resistant to erythromycin, inducibly resistant to clindamycin and susceptible to penicillin and tetracycline (adapted from PMID 18070957). (HAMAP: STRZA) |
Taxonomy | |
Kingdom: | Bacteria |
Phylum: | Firmicutes |
Class: | Bacilli |
Order: | Lactobacillales |
Family: | Streptococcaceae |
Genus: | Streptococcus |
Species: | pneumoniae |
Strain | AP200 |
Complete | Yes |
Sequencing centre | (14-SEP-2010) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA (16-JUL-2010) ITB, CNR, via F.lli Cervi 93, Segrate - Milan 20090, Italy |
Sequencing quality | Level 6: Finished |
Sequencing depth | NA |
Sequencing method | NA |
Isolation site | clinical isolate from the cerebrospinal fluid of a patient with meningitis in Italy in 2003 |
Isolation country | Italy |
Number of replicons | 1 |
Gram staining properties | Positive |
Shape | Cocci |
Mobility | No |
Flagellar presence | No |
Number of membranes | 1 |
Oxygen requirements | Facultative |
Optimal temperature | NA |
Temperature range | Mesophilic |
Habitat | HostAssociated |
Biotic relationship | NA |
Host name | Homo sapiens |
Cell arrangement | Chains, Pairs, Singles |
Sporulation | Nonsporulating |
Metabolism | NA |
Energy source | NA |
Diseases | Pneumonia |
Pathogenicity | Yes |
Glycolysis / Gluconeogenesis
Pentose phosphate pathway
Galactose metabolism
Purine metabolism
Pyrimidine metabolism
Alanine, aspartate and glutamate metabolism
Valine, leucine and isoleucine biosynthesis
Lysine biosynthesis
Phenylalanine, tyrosine and tryptophan biosynthesis
Selenocompound metabolism
D-Glutamine and D-glutamate metabolism
D-Alanine metabolism
Peptidoglycan biosynthesis
Pyruvate metabolism
C5-Branched dibasic acid metabolism
One carbon pool by folate
Thiamine metabolism
Riboflavin metabolism
Pantothenate and CoA biosynthesis
Folate biosynthesis
Terpenoid backbone biosynthesis
Aminoacyl-tRNA biosynthesis
Pentose phosphate pathway
Galactose metabolism
Purine metabolism
Pyrimidine metabolism
Alanine, aspartate and glutamate metabolism
Valine, leucine and isoleucine biosynthesis
Lysine biosynthesis
Phenylalanine, tyrosine and tryptophan biosynthesis
Selenocompound metabolism
D-Glutamine and D-glutamate metabolism
D-Alanine metabolism
Peptidoglycan biosynthesis
Pyruvate metabolism
C5-Branched dibasic acid metabolism
One carbon pool by folate
Thiamine metabolism
Riboflavin metabolism
Pantothenate and CoA biosynthesis
Folate biosynthesis
Terpenoid backbone biosynthesis
Aminoacyl-tRNA biosynthesis