Corynebacterium pseudotuberculosis FRC41

Corynebacterium_pseudotuberculosis
Names Corynebacterium pseudotuberculosis FRC41
Accession numbers NC_014329
Background Corynebacterium pseudotuberculosis is a facultative intracellular pathogen that causes caseous lymphadenitis (CLA, also known as cheesy gland) disease in sheep, goats and other small ruminants worldwide. CLA causes reduction of wool, meat and milk yields, decreased fertility, increased culling and condemnation of skins and carcasses in slaughter houses. Once established in a herd or flock, CLA eradication is problematic due to the inefficacy of antimicrobial therapy. C.pseudotuberculosis exhibits pleomorphic forms, such as coccoids and filamentous rods, ranging in size from 0.5 um to 0.6 um by 1.0 um to 3.0 um. It is a non-sporulating, non-capsulated and non-motile bacterium; however, it has fimbriae. This bacterium is a facultative anaerobe and grows best at 37 degrees Celsius, at a pH of 7.0 to 7.2. It was first isolated in 1888 and fully described in 1894. It is able to survive in the environment for a few weeks, which helps it spread within herds and flocks, infection seems to occur through contamination of wounds. It very occasionally infects humans (adapted from PMID 16472520). (EBI Integr8)
Taxonomy
Kingdom:Bacteria
Phylum:Actinobacteria
Class:Actinobacteria
Order:Actinomycetales
Family:Corynebacteriaceae
Genus:Corynebacterium
Species:pseudotuberculosis
Strain FRC41
Complete Yes
Sequencing centre (08-JUL-2010) CeBiTec, Bielefeld University, Universitaestrasse 27, Bielefeld 33615, Germany
(16-JUL-2010) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA
Sequencing quality Level 6: Finished
Sequencing depth NA
Sequencing method 454-GS-FLX
Isolation site inguinal lymph node of a 12-year-old girl with necrotizing lymphadenitis
Isolation country NA
Number of replicons 1
Gram staining properties Positive
Shape Bacilli
Mobility No
Flagellar presence No
Number of membranes 1
Oxygen requirements Facultative
Optimal temperature NA
Temperature range Mesophilic
Habitat HostAssociated
Biotic relationship NA
Host name Homo sapiens
Cell arrangement Singles
Sporulation Nonsporulating
Metabolism NA
Energy source Chemoorganotroph
Diseases NA
Pathogenicity Rarely