Dehalogenimonas lykanthroporepellens BL-DC-9

Dehalogenimonas_lykanthroporepellens
Names Dehalogenimonas lykanthroporepellens BL-DC-9
Accession numbers NC_014314
Background Dehalogenimonas lykanthroporepellens (strain ATCC BAA-1523 / JCM 15061 / BL-DC-9) is a strictly anaerobic, reductively dechlorinating Gram-negative bacterium isolated from groundwater at a superfund (law designs to clean up sites contaminated with hazardous substances) site located near Baton Rouge, USA, in an area contaminated by high concentrations of several chlorinated alkanes and alkenes. Using H2 as an electron donor, D. lykanthroporepellens couples cell growth to reductive dechlorination of 1,2,3-trichloropropane (1,2,3-TCP), a toxic and likely carcinogenic compound. It also couples cell growth to reductive dihaloelimination reactions involving a variety of other polychlorinated aliphatic alkanes. 1,2-dichloropropane (1,2-DCP) is transformed to propene, 1,2-dichloroethane (1,2-DCA) is transformed to ethene, 1,1,2-trichloroethane (1,1,2-TCA) is transformed to vinyl chloride, 1,1,2,2-TeCA is transformed to a mixture of cis- and trans-dichloroethene (DCE). Unlike some other reductively dehalogenating bacteria, in all of the reductive dechlorination reactions characterized to date, D. lykanthroporepellens appears to exclusively utilize vicinally chlorinated alkanes as electron acceptors via dihaloelimination reactions. Sequencing the genome of D. lykanthroporepellens expands the scientific understanding needed to support the incorporation of biological processes into decision making for environmental remediation and/or long-term stewardship, particularly at sites contaminated with chlorinated alkanes. At present, enzymes and metabolic pathways associated with reductive dehalogenation of chlorinated alkanes remain largely unknown, hampering use of DNA-based approaches in decision-making regarding several environmentally important contaminants (e.g., 1,2,3-TCP, 1,2-DCA). (adapted from PMID: http://genome.jgi-psf.org/dehly/dehly.home.html). (EBI Integr8)
Taxonomy
Kingdom:Bacteria
Phylum:Chloroflexi
Class:Dehalococcoidetes
Order:NA
Family:NA
Genus:Dehalogenimonas
Species:lykanthroporepellens
Strain BL-DC-9
Complete Yes
Sequencing centre (21-JUN-2010) US DOE Joint Genome Institute, 2800 Mitchell Drive B310, Walnut Creek, CA 94598-1698, USA
(30-JUN-2010) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA
Sequencing quality Level 6: Finished
Sequencing depth NA
Sequencing method NA
Isolation site NA
Isolation country NA
Number of replicons 1
Gram staining properties Negative
Shape NA
Mobility No
Flagellar presence No
Number of membranes 1
Oxygen requirements Anaerobic
Optimal temperature NA
Temperature range Mesophilic
Habitat NA
Biotic relationship Free living
Host name NA
Cell arrangement NA
Sporulation NA
Metabolism NA
Energy source NA
Diseases NA
Pathogenicity No