Streptococcus pneumoniae TCH8431/19A

Names Streptococcus pneumoniae TCH8431/19A
Accession numbers NC_014251
Background A Gram-positive nonmotile bacterium, Streptococcus pneumoniae is the most common bacterial cause of acute respiratory infection and otitis media, and is estimated to result in over 1 millions deaths in children, the elderly, debilitated and immunosuppressed people every year. Since 1990 the number of penicillin-resistant strains has increased and many strains are now resistant to commonly prescribed antibiotics such as penicillin, macrolides and fluoroquinones. Strain AP200 is a clinical strain isolated in Italy in 2003 from the cerebrospinal fluid of a patient with meningitis. It is serotype 11A and sequence type (ST) 2003, which is a single-locus variant of ST62. It is resistant to erythromycin, inducibly resistant to clindamycin and susceptible to penicillin and tetracycline (adapted from PMID 18070957). (EBI Integr8)
Strain TCH8431/19A
Complete Yes
Sequencing centre (15-JUN-2010) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA
(25-MAR-2010) Human Genome Sequencing Center, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA
Sequencing quality Level 6: Finished
Sequencing depth NA
Sequencing method Sanger, 454-GS-FLX
Isolation site respiratory tract
Isolation country NA
Number of replicons 1
Gram staining properties Positive
Shape Cocci
Mobility No
Flagellar presence No
Number of membranes 1
Oxygen requirements Facultative
Optimal temperature NA
Temperature range Mesophilic
Habitat HostAssociated
Biotic relationship Free living
Host name Homo sapiens
Cell arrangement Chains, Pairs
Sporulation Nonsporulating
Metabolism NA
Energy source NA
Diseases NA
Pathogenicity Yes