Waddlia chondrophila WSU 86-1044

Names Waddlia chondrophila WSU 86-1044
Accession numbers NC_014225, NC_014226
Background This obligatory intracellular bacteria is suspected to be an agent of miscarriage in humans and ruminants. Strain WSU 86-1044 was isolated in 1986 at the Washington Animal Disease Diagnostic Laboratory (hence the genus name) from tissues of a first-trimester aborted bovine foetus; it grows in macrophages as well as in Acanthamoeba castellanii. Unlike other Chlamydia sequenced to date 5% of the genome encodes repetitive sequences; other Chlamydia have almost no repetitive DNA. It encodes a number of virulence factors specific for resistance to host or environmental stresses including a putative carbonate permease, heavy metal exporters and multidrug efflux pumps. It is less metabolically dependent on its host than other Chlamydiae, as it encodes the capacity to synthesize some nucleotides, amino acids, lipids and other cofactors (adapted from PMID 20531937). (EBI Integr8)
Strain WSU 86-1044
Complete Yes
Sequencing centre (07-JUN-2010) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA
(09-FEB-2010) Institute of Microbiology, University Hospital Center and University of Lausanne, Bugnon 48, Lausanne VD
Sequencing quality Level 6: Finished
Sequencing depth NA
Sequencing method Solexa, Illumina GAii, 454-GS-FLX
Isolation site Pooled liver/lung homogenate from the aborted fetus of a 19-month-old primigravid Holstein cow during month 3 of gestation
Isolation country NA
Number of replicons 2
Gram staining properties Negative
Shape NA
Mobility No
Flagellar presence No
Number of membranes 2
Oxygen requirements NA
Optimal temperature NA
Temperature range NA
Habitat HostAssociated
Biotic relationship NA
Host name Cow
Cell arrangement NA
Sporulation NA
Metabolism NA
Energy source NA
Diseases NA
Pathogenicity Yes