Yersinia pestis Z176003

Yersinia_pestis
Names Yersinia pestis Z176003
Accession numbers NC_014017, NC_014022, NC_014027, NC_014029
Background Gram-negative straight rods, sometimes approaching a spherical shape. Y.pestis is always nonmotile. It is the causative agent of plague which is primarily a disease of wild rodents. Y.pestis is transmitted among wild rodents by fleas, in which the bacteria multiply and block the esophagus and the pharynx. The fleas regurgitate the bacteria when they take their next blood meal. Bacteria are transmitted subcutaneously to humans by the bite of infected fleas, but also by air, especially during pandemics of disease. Infective flea bites produce the typical bubonic form of plague in humans. Y.pestis is very closely related to the gastrointestinal pathogen Yersinia pseudotuberculosis, and it has been proposed that Y.pestis evolved from Y.pseudotuberculosis 1,500-20,000 years ago.Strain Z176003 was isolated from Marmota himalayana (Himalayan marmot) in 1976 in Naqu County, Tibet. Analysis has suggested the Yulong strains (the origin of modern plague) were closely related to the strains from the Qinghai- Tibet Plateau plague foci (adapted from PMID 20453098). (HAMAP: YERPZ)
Taxonomy
Kingdom:Bacteria
Phylum:Proteobacteria
Class:Gammaproteobacteria
Order:Enterobacteriales
Family:Enterobacteriaceae
Genus:Yersinia
Species:pestis
Strain Z176003
Complete Yes
Sequencing centre (02-JUL-2010) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA
(15-JAN-2009) State Key Laboratory for Infectious Disease Prevention and Control, Institute for Communicable Disease Control
Sequencing quality Level 6: Finished
Sequencing depth NA
Sequencing method Sanger
Isolation site dead marmot in Tibet Autonomous Region, China
Isolation country China
Number of replicons 4
Gram staining properties Negative
Shape Bacilli
Mobility Yes
Flagellar presence No
Number of membranes 2
Oxygen requirements Facultative
Optimal temperature NA
Temperature range Mesophilic
Habitat HostAssociated
Biotic relationship Free living
Host name Homo sapiens, Marmota himalayana
Cell arrangement Singles
Sporulation Nonsporulating
Metabolism NA
Energy source Heterotroph
Diseases NA
Pathogenicity Yes