Legionella longbeachae NSW150
Names | Legionella longbeachae NSW150 |
---|---|
Accession numbers | NC_013861, NC_014544 |
Background | Legionella longbeachae is one species of the family Legionellaceae that causes legionellosis, an atypical pneumonia that can be fatal if not promptly treated. While Legionella pneumophila is the leading cause of legionellosis in the USA and Europe, L. longbeachae is responsible for approximately 30% of legionellosis cases in Australia and New Zealand and nearly 50% Thailand. Most of the human cases of legionellosis are due to serogroup 1 (Sg1) strains. L. longbeachae is found predominantly in potting soil and is transmitted by inhalation of dust from contaminated soils, unlike L. pneumophila, which inhabits aquatic environments. The analysis and comparison of the genome sequences of four L. longbeachae genomes (only 1 is fully sequenced) together with the study of its gene expression program and virulence pattern in different infection models provides important new insight on the organism's lifestyle and virulence strategies. L. longbeachae harbors a unique repertoire of secreted substrates, many of which encode eukaryotic like domains that may help the pathogen to subvert host functions and cause disease. L. longbeachae may also be able to interact with plants; as several proteins present mainly in plants and phytopathogenic bacteria and several enzymes that might confer the ability to degrade plant material were identified in its genome. Interestingly, L. longbeachae encodes a chemotaxis system but no flagella, while in contrast L. pneumophila encodes flagella but no chemotaxis system (adapted from PMID 20174605). (EBI Integr8) |
Taxonomy | |
Kingdom: | Bacteria |
Phylum: | Proteobacteria |
Class: | Gammaproteobacteria |
Order: | Legionellales |
Family: | Legionellaceae |
Genus: | Legionella |
Species: | longbeachae |
Strain | NSW150 |
Complete | Yes |
Sequencing centre | (06-JAN-2010) Rusniok C., Unite de Biologie des Bacteries Intracellulaires, Institut Pasteur, 25, 28 rue du Docteur Roux, (17-FEB-2010) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA |
Sequencing quality | Level 6: Finished |
Sequencing depth | NA |
Sequencing method | Illumina GAii |
Isolation site | NA |
Isolation country | Australia |
Number of replicons | 2 |
Gram staining properties | Negative |
Shape | Bacilli |
Mobility | Yes |
Flagellar presence | No |
Number of membranes | 2 |
Oxygen requirements | Aerobic |
Optimal temperature | NA |
Temperature range | Mesophilic |
Habitat | HostAssociated |
Biotic relationship | Free living |
Host name | Homo sapiens |
Cell arrangement | Singles |
Sporulation | Nonsporulating |
Metabolism | NA |
Energy source | Chemoorganotroph |
Diseases | NA |
Pathogenicity | Yes |
Glycolysis / Gluconeogenesis
Citrate cycle (TCA cycle)
Pentose phosphate pathway
Fatty acid biosynthesis
Fatty acid metabolism
Synthesis and degradation of ketone bodies
Purine metabolism
Pyrimidine metabolism
Alanine, aspartate and glutamate metabolism
Glycine, serine and threonine metabolism
Valine, leucine and isoleucine degradation
Valine, leucine and isoleucine biosynthesis
Arginine and proline metabolism
Histidine metabolism
Phenylalanine, tyrosine and tryptophan biosynthesis
Taurine and hypotaurine metabolism
Selenocompound metabolism
Cyanoamino acid metabolism
D-Glutamine and D-glutamate metabolism
D-Alanine metabolism
Lipopolysaccharide biosynthesis
Peptidoglycan biosynthesis
Pyruvate metabolism
Butanoate metabolism
One carbon pool by folate
Thiamine metabolism
Riboflavin metabolism
Vitamin B6 metabolism
Nicotinate and nicotinamide metabolism
Pantothenate and CoA biosynthesis
Biotin metabolism
Lipoic acid metabolism
Folate biosynthesis
Aminoacyl-tRNA biosynthesis
Citrate cycle (TCA cycle)
Pentose phosphate pathway
Fatty acid biosynthesis
Fatty acid metabolism
Synthesis and degradation of ketone bodies
Purine metabolism
Pyrimidine metabolism
Alanine, aspartate and glutamate metabolism
Glycine, serine and threonine metabolism
Valine, leucine and isoleucine degradation
Valine, leucine and isoleucine biosynthesis
Arginine and proline metabolism
Histidine metabolism
Phenylalanine, tyrosine and tryptophan biosynthesis
Taurine and hypotaurine metabolism
Selenocompound metabolism
Cyanoamino acid metabolism
D-Glutamine and D-glutamate metabolism
D-Alanine metabolism
Lipopolysaccharide biosynthesis
Peptidoglycan biosynthesis
Pyruvate metabolism
Butanoate metabolism
One carbon pool by folate
Thiamine metabolism
Riboflavin metabolism
Vitamin B6 metabolism
Nicotinate and nicotinamide metabolism
Pantothenate and CoA biosynthesis
Biotin metabolism
Lipoic acid metabolism
Folate biosynthesis
Aminoacyl-tRNA biosynthesis
NCBI Genomes
NC_013861NC_014544