Legionella longbeachae NSW150

Legionella_longbeachae
Names Legionella longbeachae NSW150
Accession numbers NC_013861, NC_014544
Background Legionella longbeachae is one species of the family Legionellaceae that causes legionellosis, an atypical pneumonia that can be fatal if not promptly treated. While Legionella pneumophila is the leading cause of legionellosis in the USA and Europe, L. longbeachae is responsible for approximately 30% of legionellosis cases in Australia and New Zealand and nearly 50% Thailand. Most of the human cases of legionellosis are due to serogroup 1 (Sg1) strains. L. longbeachae is found predominantly in potting soil and is transmitted by inhalation of dust from contaminated soils, unlike L. pneumophila, which inhabits aquatic environments. The analysis and comparison of the genome sequences of four L. longbeachae genomes (only 1 is fully sequenced) together with the study of its gene expression program and virulence pattern in different infection models provides important new insight on the organism's lifestyle and virulence strategies. L. longbeachae harbors a unique repertoire of secreted substrates, many of which encode eukaryotic like domains that may help the pathogen to subvert host functions and cause disease. L. longbeachae may also be able to interact with plants; as several proteins present mainly in plants and phytopathogenic bacteria and several enzymes that might confer the ability to degrade plant material were identified in its genome. Interestingly, L. longbeachae encodes a chemotaxis system but no flagella, while in contrast L. pneumophila encodes flagella but no chemotaxis system (adapted from PMID 20174605). (EBI Integr8)
Taxonomy
Kingdom:Bacteria
Phylum:Proteobacteria
Class:Gammaproteobacteria
Order:Legionellales
Family:Legionellaceae
Genus:Legionella
Species:longbeachae
Strain NSW150
Complete Yes
Sequencing centre (06-JAN-2010) Rusniok C., Unite de Biologie des Bacteries Intracellulaires, Institut Pasteur, 25, 28 rue du Docteur Roux,
(17-FEB-2010) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA
Sequencing quality Level 6: Finished
Sequencing depth NA
Sequencing method Illumina GAii
Isolation site NA
Isolation country Australia
Number of replicons 2
Gram staining properties Negative
Shape Bacilli
Mobility Yes
Flagellar presence No
Number of membranes 2
Oxygen requirements Aerobic
Optimal temperature NA
Temperature range Mesophilic
Habitat HostAssociated
Biotic relationship Free living
Host name Homo sapiens
Cell arrangement Singles
Sporulation Nonsporulating
Metabolism NA
Energy source Chemoorganotroph
Diseases NA
Pathogenicity Yes