Streptococcus mitis B6

Streptococcus_mitis
Names Streptococcus mitis B6
Accession numbers NC_013853
Background Streptococcus mitis (strain B6) is a commensal Gram-positive normally found in the human mouth, throat and nasopharynx. It is not usually pathogenic but can be recovered from ulcerated teeth, sinuses and blood or heart lesions from subacute endocarditis (inflammation of the membrane lining the heart) patients. It is an unusually high-level beta-lactam resistant and multiple antibiotic resistant strain, which is part of the Mitis group of Gram positive bacteria that include one of the major human pathogens Streptococcus pneumoniae. Most of the genes involved in the pathogenicity such as pneumococcal virulence factors, the surface proteins implicated in host cell interaction and choline containing teichoic acids which are the anchor structure of choline binding proteins (CBPs) and host pathogen interactions, appear to be absent from S. mitis. (Adapted from PMID: 201395536). (EBI Integr8)
Taxonomy
Kingdom:Bacteria
Phylum:Firmicutes
Class:Bacilli
Order:Lactobacillales
Family:Streptococcaceae
Genus:Streptococcus
Species:mitis
Strain B6
Complete Yes
Sequencing centre (12-NOV-2009) Nuhn M., Department of Microbiology, University of Kaiserslautern, Paul-Ehrlich-Strasse, 67663
(17-FEB-2010) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA
Sequencing quality Level 6: Finished
Sequencing depth NA
Sequencing method Sanger
Isolation site hospital in Bochum, Germany
Isolation country Germany
Number of replicons 1
Gram staining properties Positive
Shape Cocci
Mobility No
Flagellar presence No
Number of membranes 1
Oxygen requirements Aerobic
Optimal temperature NA
Temperature range Mesophilic
Habitat HostAssociated
Biotic relationship Free living
Host name Homo sapiens
Cell arrangement Chains, Pairs
Sporulation Nonsporulating
Metabolism NA
Energy source NA
Diseases Bacterial endocarditis
Pathogenicity No