Fusobacterium nucleatum subsp. nucleatum ATCC 25586
Names | Fusobacterium nucleatum subsp. nucleatum ATCC 25586 |
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Accession numbers | NC_003454 |
Background | Fusobacterium nucleatum, is an anaerobic Gram-negative non-sporeforming oral bacterium found in the normal flora of the mouth, that plays a role in periodontal disease.The cells of F. nucleatum are spindle-shaped or fusiform rods of variable length. All strains obtain energy from the fermentation of sugars or amino acids, and produce butyric acid as a major metabolic by-product.Although F. nucleatum is not considered a major dental pathogen on its own, it can adhere to a wide range of other plague organisms, such as Porphyromonas gingivalis, and contribute to the development of periodontitis as well as invasive human infections of the head and neck, chest, lung, liver and abdomen. (From http://www.ebi.ac.uk/2can/genomes/bacteria.html) (BacMap) |
Taxonomy | |
Kingdom: | Bacteria |
Phylum: | Fusobacteria |
Class: | Fusobacteria |
Order: | Fusobacteriales |
Family: | Fusobacteriaceae |
Genus: | Fusobacterium |
Species: | nucleatum |
Strain | ATCC 25586 |
Complete | Yes |
Sequencing centre | (13-FEB-2002) Integrated Genomics, 2201 W. Campbell Park Drive, Chicago, IL 60612, USA (25-MAR-2002) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA |
Sequencing quality | Level 6: Finished |
Sequencing depth | NA |
Sequencing method | NA |
Isolation site | Cervico-facial lesion |
Isolation country | NA |
Number of replicons | 1 |
Gram staining properties | Negative |
Shape | Bacilli |
Mobility | No |
Flagellar presence | No |
Number of membranes | 2 |
Oxygen requirements | Anaerobic |
Optimal temperature | 37.0 |
Temperature range | Mesophilic |
Habitat | HostAssociated |
Biotic relationship | Free living |
Host name | Homo sapiens |
Cell arrangement | NA |
Sporulation | Nonsporulating |
Metabolism | NA |
Energy source | NA |
Diseases | Periodontal diseases and some inflammations |
Pathogenicity | Yes |
Glycolysis / Gluconeogenesis
Purine metabolism
Pyrimidine metabolism
Alanine, aspartate and glutamate metabolism
Cysteine and methionine metabolism
Selenocompound metabolism
D-Glutamine and D-glutamate metabolism
D-Alanine metabolism
Streptomycin biosynthesis
Lipopolysaccharide biosynthesis
Peptidoglycan biosynthesis
One carbon pool by folate
Thiamine metabolism
Riboflavin metabolism
Pantothenate and CoA biosynthesis
Biotin metabolism
Folate biosynthesis
Porphyrin and chlorophyll metabolism
Terpenoid backbone biosynthesis
Aminoacyl-tRNA biosynthesis
Purine metabolism
Pyrimidine metabolism
Alanine, aspartate and glutamate metabolism
Cysteine and methionine metabolism
Selenocompound metabolism
D-Glutamine and D-glutamate metabolism
D-Alanine metabolism
Streptomycin biosynthesis
Lipopolysaccharide biosynthesis
Peptidoglycan biosynthesis
One carbon pool by folate
Thiamine metabolism
Riboflavin metabolism
Pantothenate and CoA biosynthesis
Biotin metabolism
Folate biosynthesis
Porphyrin and chlorophyll metabolism
Terpenoid backbone biosynthesis
Aminoacyl-tRNA biosynthesis