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The map label for this gene is virS [H]

Identifier: 99081037

GI number: 99081037

Start: 1286849

End: 1287859

Strand: Direct

Name: virS [H]

Synonym: TM1040_1196

Alternate gene names: 99081037

Gene position: 1286849-1287859 (Clockwise)

Preceding gene: 99081036

Following gene: 99081038

Centisome position: 40.2

GC content: 59.15

Gene sequence:

>1011_bases
ATGCCAACCGTGACCAATGCTTTTGCGCGCGCCATGGCCCAAGCGGGCGGGATGACGCTGACCGACGATGGAGAGCTGAT
CTCTGGCGGTACTGTGGTGCGCCGACTTCCCAAACCTGCTGATGGCAAACTCTCTGAGACCGATTATTTCGATCTTCTGG
ATTGGATCCGGTTCCAGCAAAAGGACGAGATGGCACTGCTTGCGGCCTATGCCAAACTGATCCGGGCGGATGATATTGGT
GTGCTGGGCCTTGCGATGAAAACCGCGCCAACCCTGCGGGCATCGCTCGAACGTTTGGAACGGTATTGGCAGGTTGTCAC
GGATACTGCGATCTATCGACTGGACACCTCCCAAGATCCGGCGCTCTTGATCTTTGAGGCGCGCACGGGGCATCATCCTG
TGCTGGATTTTCGCAACGAGGGCGCCTTTGCCGGATTGGCACGGAATATGCGTCTGTTTGTCGAGGGGGATCTGGTTCTG
GACTATGTCACCTTCAGACATGCCTGCCGCAGCGATCCAGAGCAGTACCAGGCGCATTTTGGCTGTTCCGTCCGCTTTGA
TGCGGAGCAAAACGTCATCGCGCTGCGCAAAGAGATGCTTGATCTGCCAAACCGGTTGGGCGATGCGGCGGTTTCGGACT
TTCTGACCACGCACTTAGAGACCGAGATAGGCACGCTACAGGATGAAACCTCGGTACGTGCGGGGCTTTTGCGACTGTTG
ACGCCTGCGCTCAGTAACGGGGTGCCGCAGGCCGCAGATGTGGCCCGCGAGATGGGCATGAGCGAGCGCACGCTCTACCG
GCGCCTTGCGGACGAGGGGCTTACGTTTCGCGACGTGCTGACCGAAGCTCAGTCGTCTCTGGCGCAGGAGCTTTTGAAAG
ACAGCCGCAGCTCGATCGCGGAGATCGCCTTTTTGACCGGGTTTTCGGAGCAGAGCACCTTTAGCCGTGCCTTCAAGCGC
TGGGTCGGGCAAGCGCCAGCGCAGTTTCGACAGCAGTTCCCATCGCCCTGA

Upstream 100 bases:

>100_bases
GGACGCATGTGAGCGCGAACAGCGAGGATAATCGCGCAGCGCCTGCAAAAATCACGGTGAATAACTAGCGCTTGAGATAT
GTTTCAGATTAGTTTGGCGC

Downstream 100 bases:

>100_bases
TCGCGATTGCTCGCGTATAGTGCACGCGGCCTCTGGCCCCGGCGGTCTATCAGGCACGCGATGCTCGCGCCCAATTGAAA
CCCTCTCAACTCAGGGGGCT

Product: AraC family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 336; Mature: 335

Protein sequence:

>336_residues
MPTVTNAFARAMAQAGGMTLTDDGELISGGTVVRRLPKPADGKLSETDYFDLLDWIRFQQKDEMALLAAYAKLIRADDIG
VLGLAMKTAPTLRASLERLERYWQVVTDTAIYRLDTSQDPALLIFEARTGHHPVLDFRNEGAFAGLARNMRLFVEGDLVL
DYVTFRHACRSDPEQYQAHFGCSVRFDAEQNVIALRKEMLDLPNRLGDAAVSDFLTTHLETEIGTLQDETSVRAGLLRLL
TPALSNGVPQAADVAREMGMSERTLYRRLADEGLTFRDVLTEAQSSLAQELLKDSRSSIAEIAFLTGFSEQSTFSRAFKR
WVGQAPAQFRQQFPSP

Sequences:

>Translated_336_residues
MPTVTNAFARAMAQAGGMTLTDDGELISGGTVVRRLPKPADGKLSETDYFDLLDWIRFQQKDEMALLAAYAKLIRADDIG
VLGLAMKTAPTLRASLERLERYWQVVTDTAIYRLDTSQDPALLIFEARTGHHPVLDFRNEGAFAGLARNMRLFVEGDLVL
DYVTFRHACRSDPEQYQAHFGCSVRFDAEQNVIALRKEMLDLPNRLGDAAVSDFLTTHLETEIGTLQDETSVRAGLLRLL
TPALSNGVPQAADVAREMGMSERTLYRRLADEGLTFRDVLTEAQSSLAQELLKDSRSSIAEIAFLTGFSEQSTFSRAFKR
WVGQAPAQFRQQFPSP
>Mature_335_residues
PTVTNAFARAMAQAGGMTLTDDGELISGGTVVRRLPKPADGKLSETDYFDLLDWIRFQQKDEMALLAAYAKLIRADDIGV
LGLAMKTAPTLRASLERLERYWQVVTDTAIYRLDTSQDPALLIFEARTGHHPVLDFRNEGAFAGLARNMRLFVEGDLVLD
YVTFRHACRSDPEQYQAHFGCSVRFDAEQNVIALRKEMLDLPNRLGDAAVSDFLTTHLETEIGTLQDETSVRAGLLRLLT
PALSNGVPQAADVAREMGMSERTLYRRLADEGLTFRDVLTEAQSSLAQELLKDSRSSIAEIAFLTGFSEQSTFSRAFKRW
VGQAPAQFRQQFPSP

Specific function: May have a role in the regulation of proteins necessary for virulence [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH araC/xylS-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR018060 [H]

Pfam domain/function: PF00165 HTH_AraC [H]

EC number: NA

Molecular weight: Translated: 37430; Mature: 37299

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: PS01124 HTH_ARAC_FAMILY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPTVTNAFARAMAQAGGMTLTDDGELISGGTVVRRLPKPADGKLSETDYFDLLDWIRFQQ
CCCHHHHHHHHHHHHCCCEECCCCCEECCCHHHHHCCCCCCCCCCCCHHHHHHHHHHHCC
KDEMALLAAYAKLIRADDIGVLGLAMKTAPTLRASLERLERYWQVVTDTAIYRLDTSQDP
CCHHHHHHHHHHHHHCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHEEEECCCCCC
ALLIFEARTGHHPVLDFRNEGAFAGLARNMRLFVEGDLVLDYVTFRHACRSDPEQYQAHF
EEEEEECCCCCCCCEEECCCCCHHHHHCCCEEEEECCHHHHHHHHHHHHCCCHHHHHHHC
GCSVRFDAEQNVIALRKEMLDLPNRLGDAAVSDFLTTHLETEIGTLQDETSVRAGLLRLL
CCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
TPALSNGVPQAADVAREMGMSERTLYRRLADEGLTFRDVLTEAQSSLAQELLKDSRSSIA
HHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
EIAFLTGFSEQSTFSRAFKRWVGQAPAQFRQQFPSP
HHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHCCCC
>Mature Secondary Structure 
PTVTNAFARAMAQAGGMTLTDDGELISGGTVVRRLPKPADGKLSETDYFDLLDWIRFQQ
CCHHHHHHHHHHHHCCCEECCCCCEECCCHHHHHCCCCCCCCCCCCHHHHHHHHHHHCC
KDEMALLAAYAKLIRADDIGVLGLAMKTAPTLRASLERLERYWQVVTDTAIYRLDTSQDP
CCHHHHHHHHHHHHHCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHEEEECCCCCC
ALLIFEARTGHHPVLDFRNEGAFAGLARNMRLFVEGDLVLDYVTFRHACRSDPEQYQAHF
EEEEEECCCCCCCCEEECCCCCHHHHHCCCEEEEECCHHHHHHHHHHHHCCCHHHHHHHC
GCSVRFDAEQNVIALRKEMLDLPNRLGDAAVSDFLTTHLETEIGTLQDETSVRAGLLRLL
CCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
TPALSNGVPQAADVAREMGMSERTLYRRLADEGLTFRDVLTEAQSSLAQELLKDSRSSIA
HHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
EIAFLTGFSEQSTFSRAFKRWVGQAPAQFRQQFPSP
HHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8472958; 9634230; 12218036 [H]